Table 1

Subject characteristics at 20 year follow-up according to GBTM physical activity trajectories (n=3231)

CharacteristicLow decreasing (n=733)Light stable (n=1649)Moderate increasing (n=849)All (n=3231)
Age, years (mean ± SD)69.4 (5.6)68.5 (5.6)67.8 (5.1)68.5 (5.5)
Manual occupation (%, n)*59.8 (438)55.6 (916)38.5 (327)52.0 (1681)
Alcohol consumption, ≥light† (%, n)54.6 (400)62.4 (1029)73.5 (591)63.5 (1178)
Current smoker (%, n)19.5 (143)10.6 (174)7.4 (63)11.8 (380)
Married (%, n)80.5 (590)85.0 (1402)86.9 (738)84.5 (2730)
Resident in southern England (%, n)*26.2 (192)36.2 (597)38.2 (324)34.5 (1113)
Waist circumference, cm (mean±SD)100.1 (11.2)96.4 (10.0)95.4 (9.5)97.0 (10.3)
LDL, mmol/L (mean±SD)3.8 (1.0)4.0 (1.0)3.9 (0.9)3.9 (1.0)
HDL, mmol/L (mean±SD)1.3 (0.3)1.3 (0.3)1.4 (0.3)1.3 (0.3)
Insulin, μ/mL (median, IQR)9.6 (8.1)8.1 (5.9)7.5 (5.4)8.2 (6.4)
SBP, mm Hg (mean±SD)148.6 (23.9)149.0 (23.8)148.0 (24.4)148.6 (24.0)
FEV1, L‡ (mean±SD)235.2 (69.5)259.6 (62.5)276.1 (61.7)258.4 (65.5)
IL-6, pg/mL (median, IQR)2.8 (2.4)2.2 (1.8)2.0 (1.5)2.2 (1.9)
vWf, IU/dL (mean±SD)148.7 (48.4)137.1 (45.0)133.6 (43.0)138.8 (45.6)
Hs-TnT, pg/mL (median, IQR)12.7 (8.1)11.4 (7.0)11.5 (6.3)11.7 (7.0)
NT-proBNP, pg/mL (median, IQR)112.0 (206.0)88.0 (136.0)78.0 (111.0)89.0 (144)
Previous MI (%, n)9.1 (67)7.3 (120)6.0 (51)7.4 (238)
Previous stroke (%, n)3.3 (24)2.4 (39)2.2 (19)2.5 (82)
Previous diabetes (%, n)14.5 (106)7.4 (122)7.0 (59)8.9 (287)
  • *Reported at baseline.

  • †light classified as ≥1 unit per week.

  • ‡Standardised for height by multiplying FEV1 by the square of the mean population height (metres) divided by each participant’s height.

  • FEV1, forced expiratory volume in 1 s;GBTM, group-based trajectory modelling; HDL, high-density lipoprotein; Hs-TnT, high-sensitivity cardiac troponin T; IL-6, interleukin 6; LDL, low-density lipoprotein; MI, myocardial infarction; NT-proBNP, N-terminal pro-brain natriuretic peptide; SBP, systolic blood pressure; vWf, von Willebrand factor.