Estimates of prevalence, relative risk of disease and PAF for sedentary behaviour in the UK
| Strength of evidence* | Health outcome | Proportion of prolonged sedentary adults in cases (%)†| RR (95% CI) | PAF, % (95% CI) |
| Strong | Type 2 diabetes | 36 | 1.88 (1.62 to 2.17) | 16.9 (14.0 to 19.6) |
| Cardiovascular disease incidence | 40 | 1.14 (1.09 to 1.19) | 4.9 (4.2 to 5.5) | |
| All-cause mortality | 60 | 1.25 (1.16 to 1.34) | 11.6 (10.3 to 12.9) | |
| Moderate | Lung cancer | 35 | 1.27 (1.06 to 1.52) | 7.5 (3.9 to 11.0) |
| Colon cancer | 39 | 1.30 (1.12 to 1.49) | 9.0 (7.3 to 10.7) | |
| Endometrial cancer | 37 | 1.28 (1.08 to 1.53) | 8.0 (6.0 to 10.0) |
*Strength of evidence as reported by the 2018 Physical Activity Guidelines Advisory Committee.
†Estimated from weekday and weekend proportions available from Health Survey for England5 and multiplied by the prevalence adjustment factor for each outcome.
RR, relative risk;PAF, population attributable fraction.