Association of 8-level life course trajectories with all-cause and cause-specific mortality in the whole study sample (n=22 194)
| All-cause mortality | CVD mortality | Cancer mortality | Other cause mortality | |||||||
| N of subjects (%) | N of events/ Rate of death (%) | Survival estimate | HR (95% CI) | N of events/ Rate of death (%) | HR (95% CI) | N of events/ Rate of death (%) | HR (95% CI) | N of events/ Rate of death (%) | HR (95% CI) | |
| High childhood SES+high education+high adult SES (stable high) | 4412 (19.9) | 113 (2.6) | 0.940 (0.929–0.952) | −1- | 36 (0.8) | −1- | 54 (1.2) | −1- | 23 (0.5) | −1- |
| High childhood SES+low education+high adult SES | 901 (4.1) | 48 (5.3) | 0.917 (0.896–0.939) | 1.45 (1.03 to 2.03) | 21 (2.3) | 1.87 (1.09 to 3.21) | 20 (2.2) | 1.32 (0.79 to 2.20) | 7 (0.8) | 1.06 (0.45 to 2.48) |
| High childhood SES+high education+low adult SES | 2886 (13.0) | 40 (1.4) | 0.938 (0.920–0.957) | 1.04 (0.72 to 1.50) | 12 (0.4) | 1.14 (0.59 to 2.21) | 25 (0.9) | 1.29 (0.79 to 2.08) | 3 (0.1) | 0.35 (0.10 to 1.16) |
| High childhood SES+low education+low adult SES | 3239 (14.6) | 132 (4.1) | 0.914 (0.899–0.929) | 1.51 (1.17 to 1.95) | 48 (1.5) | 1.61 (1.04 to 2.49) | 57 (1.8) | 1.44 (0.99 to 2.09) | 27 (0.8) | 1.54 (0.88 to 2.69) |
| Low childhood SES+high education+high adult SES | 1976 (8.9) | 115 (5.8) | 0.939 (0.927–0.950) | 1.03 (0.79 to 1.33) | 38 (1.9) | 0.96 (0.60 to 1.51) | 43 (2.2) | 0.86 (0.58 to 2.29) | 34 (1.7) | 1.55 (0.91 to 2.66) |
| Low childhood SES+low education+high adult SES | 1443 (6.5) | 149 (10.3) | 0.910 (0.896–0.925) | 1.58 (1.23 to 2.02) | 54 (3.7) | 1.57 (1.03 to 2.41) | 62 (4.3) | 1.50 (1.03 to 2.17) | 33 (2.3) | 1.82 (1.06 to 3.13) |
| Low childhood SES+high education+low adult SES | 1377 (6.2) | 49 (3.6) | 0.917 (0.895–0.939) | 1.45 (1.03 to 2.03) | 16 (1.2) | 1.54 (0.85 to 2.78) | 19 (1.4) | 1.13 (0.67 to 1.91) | 14 (1.0) | 2.09 (1.07 to 4.07) |
| Low childhood SES+low education+low adult SES (stable low) | 5960 (26.8) | 509 (8.5) | 0.911 (0.901–0.922) | 1.56 (1.26 to 1.92) | 189 (3.2) | 1.58 (1.10 to 2.27) | 173 (2.9) | 1.22 (0.89 to 1.68) | 147 (2.5) | 2.36 (1.50 to 3.72) |
Multivariable HR with 95% CI and survival estimates from the model controlled for age (ordered quintiles), sex, marital status (married/cohabiting; separated/divorced; single; widowed).
SES, socioeconomic status.