NRI by adding hs-CRP to the risk factors independently associated with CVD
| Predicted risk (without hs-CRP) | Reclassified predicted risk (with hs-CRP) | |||||
| 0%–5% | 5%–10% | ≥10% | ||||
| N | % | N | % | N | % | |
| With CVD (n=189) | ||||||
| 0%–5% | 87 | 95.6 | 9 | 16.7 | 0 | 0.0 |
| 5%–10% | 4 | 4.4 | 43 | 79.6 | 15 | 34.1 |
| ≥10% | 0 | 0.0 | 2 | 3.7 | 29 | 65.9 |
| Total | 91 | 54 | 44 | |||
| Without CVD (n=8499) | ||||||
| 0%–5% | 7136 | 98.5 | 198 | 21.7 | 0 | 0.0 |
| 5%–10% | 111 | 1.5 | 681 | 74.6 | 89 | 26.3 |
| ≥10% | 0 | 0.0 | 34 | 3.7 | 250 | 73.7 |
| Total | 7247 | 913 | 339 | |||
Estimates of probabilities using traditional risk factors (vertical axis) and with traditional variables and inclusion of hs-CRP information (horizontal axis) are shown.
CVD, cardiovascular disease; hs-CRP, high-sensitivity C-reactive protein; NRI, net reclassification improvement.