Risk drinking group | Reference group | AUDIT version | Setting | Estimates (n) | Participants (n) | Deaths (n) | Relative Risk | 95% CI | I 2 (%) | P-values for heterogeneity |
Moderate | Abstainers | Both | Both | 7 | 226 379 | 14 401 | 0.78 | 0.71 to 0.85 | 24.0 | 0.246 |
At risk | Abstainers | Both | Both | 7 | 157 400 | 11 221 | 1.18 | 0.92 to 1.52 | 75.6 | <0.001 |
At risk | Moderate | Both | Both | 9 | 190 902 | 10 484 | 1.24 | 1.12 to 1.37 | 36.7 | 0.125 |
Moderate | Abstainers | AUDIT-10 | Population | 4 | 3 980 | 279 | 0.99 | 0.72 to 1.38 | 21.5 | 0.281 |
At risk | Abstainers | AUDIT-10 | Population | 4 | 3 772 | 271 | 2.02 | 1.26 to 3.24 | 21.4 | 0.282 |
At risk | Moderate | AUDIT-10 | Population | 4 | 4 003 | 208 | 1.71 | 0.98 to 3.00 | 51.8 | 0.125 |
Moderate | Abstainers | AUDIT-C | VA | 3 | 222 399 | 14 122 | 0.75 | 0.71 to 0.79 | 0.0 | 0.909 |
At risk | Abstainers | AUDIT-C | VA | 3 | 153 628 | 10 950 | 0.91 | 0.78 to 1.06 | 63.1 | 0.067 |
At risk | Moderate | AUDIT-C* | VA | 5 | 186 899 | 10 276 | 1.21 | 1.13 to 1.30 | 20.7 | 0.283 |
Note: abstainers (past year): AUDIT-10=0 or AUDIT-C=0.
At-risk drinking: AUDIT-10: ≥8 or AUDIT-C: ≥3 or ≥4; moderate, AUDIT-10=1–7 or AUDIT-C=1–3 or 1–4.
*One study21 used AUDIT-10.