Table 3

Associations of childhood psychosocial adversity with age at menopause (n=945)

Exposure	Model 1		Model 2		Model 3
Exposure	Mean difference in years (95% CI)	P value	Mean difference in years (95% CI)	P value	Mean difference in years (95% CI)	P value
Total psychosocial adversity	0.000 (−0.290 to 0.290)	0.998	−0.010 (−0.275 to 0.255)	0.940	−0.023 (−0.286 to 0.240)	0.864
Lack of care	0.067 (−0.205 to 0.339)	0.631	0.047 (−0.198 to 0.292)	0.706	0.036 (−0.207 to 0.279)	0.770
Maladaptive family functioning	−0.103 (−0.395 to 0.189)	0.487	−0.024 (−0.287 to 0.239)	0.856	−0.021 (−0.286 to 0.244)	0.877
Non-sexual abuse	0.018 (−0.364 to 0.400)	0.927	0.004 (−0.341 to 0.349)	0.982	−0.014 (−0.343 to 0.315)	0.934
Overprotective parenting	0.061 (−0.223 to 0.345)	0.674	−0.076 (−0.339 to 0.187)	0.569	−0.090 (−0.351 to 0.171)	0.498
Parental mental illness	−0.229 (−0.613 to 0.155)	0.244	−0.111 (0.444 to 0.222)	0.514	−0.154 (−0.489 to 0.181)	0.368
Sexual abuse	−0.189 (−0.575 to 0.197)	0.338	−0.169 (−0.518 to 0.180)	0.342	−0.182 (−0.529 to 0.165)	0.304

Beta coefficients are interpreted as the mean difference in age at menopause in years per SD increase in psychosocial adversity.
Model 1: unadjusted.
Model 2: adjusted for age at recruitment and ethnicity.
Model 3: adjusted for age at recruitment, educational qualifications and ethnicity.