Table 2

Associations of childhood psychosocial adversity with age at menarche (n=8984)

Exposure	Model 1		Model 2		Model 3
Exposure	Mean difference in years (95% CI)	P value	Mean difference in years (95% CI)	P value	Mean difference in years (95% CI)	P value
Total psychosocial adversity	0.005 (−0.034 to 0.044)	0.790	0.007 (−0.032 to 0.046)	0.729	0.006 (−0.033 to 0.045)	0.778
Lack of care	0.027 (−0.008 to 0.062)	0.134	0.023 (−0.012 to 0.058)	0.198	0.022 (−0.013 to 0.057)	0.223
Maladaptive family functioning	0.013 (−0.026 to 0.052)	0.527	0.023 (−0.016 to 0.062)	0.251	0.022 (−0.017 to 0.061)	0.273
Non-sexual abuse	−0.007 (−0.056 to 0.042)	0.777	−0.003 (−0.052 to 0.046)	0.897	−0.002 (−0.051 to 0.047)	0.943
Overprotective parenting	−0.003 (−0.040 to 0.034)	0.881	−0.008 (−0.045 to 0.029)	0.671	−0.009 (−0.046 to 0.028)	0.631
Parental mental illness	−0.027 (−0.076 to 0.022)	0.280	−0.030 (−0.079 to 0.019)	0.220	−0.030 (−0.079 to 0.019)	0.220
Sexual abuse	−0.182 (−0.235 to 0.129)	<0.001	−0.172 (−0.225 to 0.119)	<0.001	−0.173 (−0.226 to 0.120)	<0.001

Beta coefficients are interpreted as a mean difference in age at menarche in years per SD increase in psychosocial adversity.
Model 1: unadjusted.
Model 2: adjusted for age at recruitment and ethnicity.
Model 3: adjusted for age at recruitment, educational qualifications and ethnicity.