Table 4

Analysis of covariate-adjusted outcome change scores for control group participants who crossed over to the intervention (n=137)

Outcome variableNPre, mean (SD)Post, mean (SD)Adjusted change, mean (SEM)p value* (one-sided)
SF-36 V. 2
 Physical function13738.90 (12.09)40.08 (12.04)1.18 (0.81)0.07
 Role physical13740.46 (10.34)42.30 (9.81)1.84 (0.95)0.03
 Bodily pain13744.40 (11.87)45.85 (11.06)1.45 (0.87)0.05
 General health13745.77 (10.09)46.03 (9.24)0.27 (0.68)0.34
 Vitality13650.19 (11.32)51.77 (9.00)1.53 (0.78)0.03
 Social function13745.18 (11.44)46.18 (9.74)1.00 (0.94)0.15
 Role emotional13740.73 (12.85)41.98 (11.49)1.25 (0.98)0.10
 Mental health13647.33 (11.90)49.62 (9.90)2.24 (0.94)0.01
 Physical composite13641.45 (9.95)42.49 (9.81)0.69 (0.64)0.07
 Mental composite13647.74 (12.26)49.42 (10.56)1.63 (0.91)0.04
Life satisfaction-Z13616.65 (5.51)17.44 (5.17)0.79 (0.37)0.02
CES-D Scale13713.39 (11.05)11.78 (9.21)−1.66 (0.76)0.01
CERAD-memory
 Immediate recall1274.60 (1.45)4.87 (1.71)0.24 (0.15)0.05
 Delayed recall1274.99 (2.17)5.77 (2.30)0.71 (0.17)<0.0001
 Recognition12718.34 (2.35)18.87 (2.25)0.49 (0.19)0.01
Visual search
 Median reaction time1161222 (407.5)1209 (433.3)−13.6 (27.50)0.31
Psychomotor speed12340.39 (17.50)42.99 (17.82)2.19 (0.96)0.01
  • Covariates were (1) cohort (1, 2), (2) age (continuous), (3) sex (male, female), (4) race (white, black, Hispanic, Other), (5) education (<high school, high school, some college, college plus), (6) site (graduated care retirement community, senior residence, senior centre—multipurpose, senior centre—parks and recreation), (7) neighbourhood score (1–7), (8) CERAD-recognition (pre-test), (9) psychomotor speed (pre-test).

  • * p Values were obtained using a mixed model with repeated measurement.

  • Reasons for not completing cognitive testing: visual or other physical impairment or scheduling conflicts.

  • CES-D Scale, Center for Epidemiologic Studies Depression Scale; CERAD, Consortium to Establish a Registry of Alzheimer's Disease; SF-36 V. 2, Version 2 of the 36-Item Short-Form Health Survey.