Table 3

Intent-to-treat analysis of outcome change scores (post-baseline) for evaluable participants stratified by intervention group (n=360)

Outcome variableIntervention groupNBaseline, mean (SD)Post, mean (SD)Adjusted change, mean (SEM)p Value* (one-sided)
SF-36 V. 2
 Physical functionTreatment18738.60 (12.06)39.84 (12.70)1.04 (0.82)0.09
Control17338.62 (12.35)38.81 (12.11)−0.12 (0.80)
 Role physicalTreatment18740.63 (11.72)40.78 (11.37)0.66 (0.82)0.18
Control17341.73 (10.10)40.72 (9.94)−0.15 (0.82)
 Bodily painTreatment18742.75 (11.60)44.62 (11.20)2.76 (0.83)0.02
Control17344.53 (11.30)44.38 (11.86)0.89 (0.82)
 General healthTreatment18744.74 (10.10)46.19 (9.85)1.14 (0.70)0.25
Control17344.75 (10.17)45.74 (10.48)0.61 (0.69)
 VitalityTreatment18750.02 (9.90)51.29 (9.85)2.31 (0.84)0.03
Control17250.06 (9.47)49.60 (11.23)0.59 (0.83)
 Social functionTreatment18744.54 (11.75)45.36 (11.37)1.05 (0.89)0.04
Control17346.57 (9.75)45.00 (11.33)−0.70 (0.88)
 Role emotionalTreatment18739.39 (14.26)40.72 (12.95)1.30 (1.03)0.16
Control17341.16 (12.07)40.69 (12.86)0.21 (1.02)
 Mental healthTreatment18747.75 (11.89)49.07 (10.70)2.31 (0.87)0.03
Control17247.48 (11.22)47.16 (11.81)0.48 (0.86)
 Physical compositeTreatment18740.83 (10.27)41.86 (10.68)1.02 (0.65)0.09
Control17241.51 (10.43)41.53 (9.99)0.07 (0.64)
 Mental compositeTreatment18747.41 (11.80)48.64 (10.63)1.79 (0.87)0.03
Control17248.28 (10.46)47.45 (12.01)0.04 (0.86)
Life satisfaction-ZTreatment18717.23 (5.68)18.00 (5.37)0.84 (0.40)0.03
Control17216.78 (5.70)16.85 (5.49)−0.02 (0.39)
CES-D ScaleTreatment18613.78 (10.80)12.47 (9.68)−1.69 (0.75)0.03
Control17312.97 (10.54)13.53 (11.17)−0.08 (0.74)
CERAD-memory
 Immediate recallTreatment1804.17 (1.74)4.45 (1.63)0.26 (0.13)0.20
Control1674.12 (1.43)4.54 (1.43)0.38 (0.13)
 Delayed recallTreatment1805.11 (2.25)5.05 (2.22)0.07 (0.15)0.38
Control1674.91 (2.18)4.86 (2.19)0.02 (0.15)
 RecognitionTreatment18018.63 (2.03)18.37 (2.44)−0.12 (0.19)0.26
Control16618.32 (2.20)18.14 (2.44)−0.16 (0.18)
Visual search
 Median reaction timeTreatment1661360 (565.4)1229 (452.1)−137 (31.61)0.49
Control1521348 (639.8)1235 (456.4)−138 (31.04)
Psychomotor speedTreatment17139.84 (16.25)41.71 (17.61)1.34 (0.89)0.49
Control16039.44 (16.55)40.21 (18.03)1.31 (0.88)
  • Covariates were (1) baseline value, (2) cohort (1, 2), (3) age (continuous), (4) sex (male, female), (5) race (white, black, Hispanic, Other), (6) education (<high school, high school, some college and college plus), (7) site (graduated care retirement community, senior residence, senior centre—multipurpose, senior centre—parks and recreation), (8) neighbourhood score (1–7), (9) CERAD-recognition, (10) psychomotor speed.

  • * p Values were obtained using analysis of covariance.

  • Reasons for not completing cognitive testing: visual or other physical impairment or scheduling conflicts.

  • CES-D Scale, Center for Epidemiologic Studies Depression Scale; CERAD, Consortium to Establish a Registry of Alzheimer's Disease; SF-36 V. 2, Version 2 of the 36-Item Short-Form Health Survey.