Table 3

Effect modification of ARV by feeding practice, birth weight, and mode of delivery on the weighted national perinatal MTCT rates, South Africa, 2010

ARVOther variableUnweighted frequencyWeighted MTCT risk estimate%95% CI
Advanced ARV regimensNo breast milk at all222.111.28 to 2.95
Exclusive BF143.941.98 to 5.90
Mixed BF72.070.55 to 3.60
Other ARV regimensNo breast milk at all162.571.31 to 3.84
Exclusive BF93.421.19 to 5.66
Mixed BF114.872.01 to 7.74
No ARVNo breast milk at all53.450.53 to 6.37
Exclusive BF911.504.67 to 18.33
Mixed BF2211.907.45 to 16.35
Advanced ARV regimensLow birth weight82.390.54 to 3.54
Normal birth weight352.491.78 to 3.33
Other ARV regimensLow birth weight109.283.81 to 14.80
Normal birth weight262.321.40 to 3.23
No ARVLow birth weight88.372.68 to 17.04
Normal birth weight289.155.69 to 12.01
Advanced ARV regimensNo C-section342.411.63 to 3.19
C-section92.721.05 to 4.38
Other ARV regimensNo C-section323.522.31 to 4.72
C-section41.770.01 to 3.53
No ARVNo C-section277.465.00 to 9.93
C-section915.186.36 to 23.99
  • Refer to figure 1 for ARV categories: advance ARV regimens=groups 1a and 1b; other ARV regimens=groups 2a and 2b; no ARV group=group 3a. Note: the missing ARV information group 3b is excluded from this analysis; Feeding=previous 8 days recall.

  • ARV, antiretroviral; BF, breast feeding; C-section, caesarean section; MTCT, mother-to-child transmission.