Table 3

IQ and case-fatality at first CHD event 1991–2008 and subsequent mortality

28-day case fatality (1991–2007)CVD mortality (mean 1919 days)All-cause mortality (mean 1816 days)
N=2156, 233 casesN=1923, 74 casesN=1923, 146 cases
OR (95% CI)HR (95% CI)HR (95% CI)
Adjusted forMedium IQLow IQMedium IQLow IQMedium IQLow IQ
Age1.33 (0.93 to 1.90)1.46 (0.98 to 2.18)1.94 (0.97 to 3.88)2.32 (1.12 to 4.85)1.74 (1.08 to 2.80)2.20 (1.33 to 3.64)
 + Early life factors (potential confounders)*1.31 (0.91 to 1.88)1.42 (0.94 to 2.14)2.01 (1.00 to 4.06)2.48 (1.17 to 5.27)1.76 (1.09 to 2.84)2.23 (1.33 to 3.73)
 + Factors in adolescence and adulthood (potential mediators)†1.06 (0.73 to 1.55)0.97 (0.62 to 1.50)1.92 (0.94 to 3.94)1.98 (0.89 to 4.37)1.63 (1.00 to 2.65)1.62 (0.94 to 2.78)
  • High IQ is the reference in all analyses.

  • *Childhood socioeconomic position, parent’s CVD death at age <65.

  • †BMI, smoking, risk use of alcohol, systolic blood pressure, occupational class, income, single household and comorbidity/complications.

  • BMI, body mass index; CHD, coronary heart disease; CVD, cardiovascular diseases.