Table 2

True ORXY, and true and observed percentage mediation of X→Y association by Z, for selected combinations of ORXY|Z, ORXZ|Y, ORYZ|X, varying ratio of Z1 to Z0 among non-cases (Y=0), and sensitivity (Se) and specificity (Sp) of Z measurement

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  • †The ‘Apparent mediation by Z, given misclassification of Z’ is 100%×(ORXY−ORXY|Z*)/(ORXY−1), where Z* refers to misclassified value of Z.

  • Web annex table 1 includes output for all possible combinations of ORXY|Z, ORXZ|Y, ORYZ|X.