Ischaemic heart disease HR in men by any alcohol use and by frequency of binge drinking
| Model 1* | Model 2† | Model 3‡ | Model 4§ | ||||
|---|---|---|---|---|---|---|---|
| N | Number of deaths | Deaths (%) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | |
| Frequency of any alcohol intake | 6349 | 395 | 6.2 | ||||
| Abstainers | 538 | 56 | 10.4 | Ref | Ref | Ref | Ref |
| ≤Twice/month | 3302 | 200 | 6.1 | 0.73 (0.54 to 0.98) | 0.75 (0.55 to 1.01) | 0.78 (0.57 to 1.05) | 0.70 (0.51 to 0.97) |
| Once a week | 1829 | 83 | 4.5 | 0.66 (0.47 to 0.93) | 0.69 (0.49 to 0.98) | 0.71 (0.50 to 1.01) | 0.62 (0.43 to 0.91) |
| 2–3 times/week | 598 | 49 | 8.2 | 1.08 (0.74 to 1.59) | 1.11 (0.75 to 1.65) | 1.14 (0.77 to 1.70) | 0.95 (0.62 to 1.47) |
| About every day | 82 | 7 | 8.5 | 1.33 (0.60 to 2.94) | 1.22 (0.55 to 2.71) | 1.23 (0.56 to 2.74) | 1.01 (0.44 to 2.28) |
| Binge drinking | |||||||
| Not last year | 1400 | 97 | 6.9 | Ref | Ref | Ref | Ref |
| A few times last year | 2733 | 159 | 5.8 | 1.08 (0.84 to 1.40) | 1.05 (0.81 to 1.36) | 1.06 (0.82 to 1.38) | 1.14 (0.87 to 1.50) |
| 1–3 times per month | 1561 | 84 | 5.4 | 1.28 (0.95 to 1.72) | 1.21 (0.89 to 1.63) | 1.23 (0.91 to 1.66) | 1.38 (0.97 to 1.95) |
| 1–2 times per week | 385 | 27 | 7.0 | 1.63 (1.06 to 2.51) | 1.54 (1.00 to 2.38) | 1.52 (0.98 to 2.36) | 1.84 (1.10 to 3.09) |
| ≥Three times per week | 98 | 10 | 10.2 | 3.09 (1.60 to 5.97) | 2.37 (1.21 to 4.62) | 2.29 (1.17 to 4.46) | 3.00 (1.39 to 6.43) |
| Frequency not reported | 172 | 18 | 10.5 | 1.25 (0.76 to 2.08) | 1.14 (0.69 to 1.89) | 1.19 (0.72 to 1.98) | 1.29 (0.77 to 2.15) |
Men aged 20–62 years, N=6349.
*Adjusted for age by stratification.
†Adjusted for age, smoking and income.
‡Adjusted in addition for baseline myocardial infarction, angina, stroke, diabetes or antihypertensive medication, angina symptoms, serum total cholesterol and systolic blood pressure.
§In analysis of mortality by frequency of any intake: adjusted in addition for binge drinking and in analysis of mortality by binge drinking adjusted for frequency of any alcohol use.