Associations between childhood cognitive ability and somatic symptoms and syndromes
| Somatic symptom scores at age 23 years | Somatic symptom scores at age 33 years | Somatic symptom scores at age 42 years | CFS/ME at age 42 years | CFS-like illness at age 42 years | IBS at age 42 years | |
|---|---|---|---|---|---|---|
| β (95% CI) | β (95% CI) | β (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
| Childhood cognitive ability† | −0.152** (−0.171 to −0.134) | −0.147** (−0.167 to −0.128) | −0.118** (−0.138 to −0.099) | 1.005 (0.992 to 1.018) | 0.962** (0.962 to 0.980) | 0.997 (0.992 to 1.002) |
| Childhood cognitive ability‡ | −0.132** (−0.154 to −0.110) | −0.077** (−0.098 to −0.057) | −0.044** (−0.064 to −0.024) | 1.011 (0.996 to 1.026) | 0.979** (0.968 to 0.990) | 1.000 (0.995 to 1.006) |
| Childhood cognitive ability§ | −0.060** (−0.081 to −0.039) | −0.031** (−0.050 to −0.011) | −0.016 (−0.034 to 0.002) | 1.017* (1.002 to 1.033) | 0.993 (0.981 to 1.005) | 1.003 (0.997 to 1.009) |
*p<0.05, **p<0.01.
†Adjusted for sex.
‡Adjusted for sex, previous somatic symptoms and internalising symptoms at age 11 years.
§In addition to the previous model adjusted for psychological symptom scores at time of outcome measure.
CFS/ME, chronic fatigue syndrome/myalgic encephalomyelitis; IBS, irritable bowel syndrome.