Table 2

Mean adjusted change in eGFR (95% CI) levels comparing patients living 50 m to patients living 1000 m from the nearest major roadway*

ModeleGFR difference (ml/min/1.73 m2)†95% CIp Value
Unadjusted−5.7−9.0 to −2.3<0.001
Adjusted for age and sex−3.8−6.7 to −0.90.01
Fully adjusted‡−3.9−6.7 to −1.00.007
  • *From a model where the natural logarithm of residential distance to major roadway was entered as a continuous variable.

  • †A negative value indicates that adjusted mean eGFR is lower among patients living 50 m than patients living 1000 m from a major roadway.

  • ‡Adjusted for age, sex, race, smoking status, diabetes, hypertension, heart failure, coronary artery disease, treatment with ACE inhibitor, median household income and percentage of residents without high school diploma.

  • eGFR, estimated glomerular filtration rate.