Table 5

Combined effect of clustering of cardiovascular risk factors* and physical activity on mortality from stroke

Clustering of cardiovascular risk factors
VariableNoYes
No activity
 No. of deaths31690
 No. person years103 2019906
 Adjusted HR (95% CI)1.00 (Reference)1.46 (1.16 to 1.85)
Less than once per week
 No. of deaths28763
 No. person years257 75314 418
 Adjusted HR (95% CI)0.96 (0.82 to 1.13)1.30 (0.99 to 1.71)
Low summary score (<median)
 No. of deaths47181
 No. person years257 52318 199
 Adjusted HR (95% CI)0.80 (0.69 to 0.92)0.88 (0.69 to 1.12)
High summary score (≥median)
 No. of deaths27447
 No. person years263 93011 008
 Adjusted HR (95% CI)0.71 (0.60 to 0.84)1.05 (0.77 to 1.43)
  • * Clustering defined as systolic blood pressure ≥130 mmHg, diastolic blood pressure ≥85 mmHg, non-fasting blood glucose ≥6 and body mass index ≥25 kg/m2.

  • Adjusted for age, sex, smoking status (never, former, current, unknown), marital status (married, unmarried, widow(er), divorced/separated, unknown), education (<9, 10–12, ≥13 y).

  • Summary score of recreational physical activity combining information on frequency, duration and intensity.