Table 2

Sensitivity and specificity of individual signs and symptoms for AIDS deaths in Manicaland and Kisesa cohorts, stratified at age 45 years

SymptomTrainTest
Manicaland phase IManicaland phase IIManicaland phase IIKisesa
15–44 years (n=237)15–59 years (n=102)15–44 years (n=180)45–59 years (n=38)15–44 years (n=158)45–59 years (n=39)
SeSpSeSpSeSpSeSpSeSpSeSp
Weight loss91001099129809110962384
Herpes zoster1293189524981910014978100
Jaundice199349741000100599896
Vaginal tumours694694310001000100096
Wasting1993199515951310016958100
ARTI1195109589513100596088
Abscesses or sores2490249229983210019968100
Oral candidiasis3886378945862691409215100
Diarrhoea179517922993231001092888
Recent TB*27862888478232100599896
  • ARTI, acute respiratory tract infections; Se, sensitivity; Sp, specificity; TB, tuberculosis.

  • * Recent tuberculosis is shown for information but was not included in the final algorithm due poor specificity.