Random effects model: years 2 to 14 inclusive | ||||||
Estimate of effects (EE) 95% CI Significance (p-value) | ||||||
Unadjusted analysis¶ | Adjusted analysis** | |||||
Predictor variables | Total behaviour | Internalising behaviour | Externalising behaviour | Total behaviour | Internalising behaviour | Externalising behaviour |
Smoking in pregnancy‡ | ||||||
1–10 cigarettes daily pre-pregnancy§ | −0.03 −0.13, 0.06 0.493 | −0.02 −0.11, 0.07 0.647 | −0.02 −0.12, 0.07 0.654 | −0.11* −0.21, −0.01 0.032 | −0.07 −0.17, 0.02 0.129 | −0.09 −0.19, 0.01 0.076 |
11+ cigarettes daily pre-pregnancy§ | 0.05 −0.05, 0.15 0.305 | 0.00 −0.09, 0.09 0.974 | 0.09 −0.00, 0.19 0.061 | −0.02 −0.13, 0.09 0.705 | −0.04 −0.14, 0.06 0.407 | 0.02 −0.09, 0.12 0.749 |
Smoked before and during pregnancy | 0.38† 0.30, 0.47 <0.001 | 0.27† 0.19, 0.35 <0.001 | 0.41† 0.33, 0.49 <0.001 | 0.16† 0.06, 0.26 0.002 | 0.10* 0.00, 0.19 0.049 | 0.21† 0.10, 0.31 <0.001 |
↵* p<0.05.
↵† p<0.005.
↵‡ Reference category never smoked.
↵§ No longer smoking by 18 weeks gestation.
↵¶ Adjusted for child's age as a random slope.
↵** Adjusted for maternal age at conception, maternal education at 18 weeks gestation, the presence of the biological father in the family home at 18 weeks gestation, family income at 18 weeks gestation, total stress events in pregnancy, alcohol intake at 18 weeks gestation, birth weight (grams), gestational age (weeks), breast feeding duration (months), family functioning from 5 to 14 years and child's age as a random slope.
CBCL, Child Behaviour Checklist.