Table 2 Long-term alcohol consumption in relation to cardiovascular and all-cause mortality within the Zutphen Study
Amount (g/day)Long-term intake (cumulative average, time-dependent)
Crude HR (95% CI)*Adjusted HR (95% CI)†‡
Coronary heart disease>0 to 200.92 (0.67 to 1.25)0.80 (0.57 to 1.11)
>200.80 (0.49 to 1.31)0.77 (0.44 to 1.33)
Cerebrovascular>0 to 200.44 (0.28 to 0.68)0.43 (0.26 to 0.70)
>200.44 (0.22 to 0.92)0.56 (0.25 to 1.25)
Total cardiovascular>0 to 200.75 (0.60 to 0.95)0.70 (0.55 to 0.89)
>200.78 (0.56 to 1.10)0.83 (0.56 to 1.22)
All cause>0 to 200.78 (0.65 to 0.93)0.75 (0.63 to 0.91)
>200.82 (0.63 to 1.07)0.82 (0.61 to 1.12)
  • *Crude HR, hazard ratio; CI, confidence interval.

  • †Hazard ratios are adjusted for former drinking, energy intake without alcohol, the number of cigarettes smoked, cigarette smoking duration, cigar or pipe smoking, intake of vegetables, fruit, fish, saturated fat and trans fatty acids, body mass index, prevalence of myocardial infarction, stroke, diabetes mellitus and cancer, and baseline socioeconomic status.

  • ‡Because of missing data in the covariates, the number of events is less than the number mentioned in table 1.