Table 1

Distribution of demographic and clinical variables for the cohort of 681 patients by whether they presented tuberculosis recurrence or not and the probability (raw risk) of having tuberculosis recurrence, Barcelona 1995–2005

VariablesRecurrence 29 (4.3%)No recurrence 652 (95.7%)HR (95% CI)p value
Sex
    Female3 (10.3)217 (33.3)1 (–)
    Male26 (89.7)435 (66.7)4.3 (1.3 to 14.3)0.016
Age (median and IQR)34 (25.5 to 38.5)36 (28 to 52)0.98 (0.97 to 1.01)0.12
Country
    Autochthonous24 (82.8)603 (92.5)1 (–)
    Foreign born5 (17.2)49 (7.5)2.5 (0.94 to 6.5)0.06
IDU
    No18 (62.1)554 (85)1 (–)
    Yes11 (37.9)98 (15)3.6 (1.7 to 7.6)0.001
HIV positive
    No17 (58.6)512 (78.5)1(–)
    Yes12 (41.4)136 (20.9)2.8 (1.3 to 5.8)0.007
    Unknown0 (0)4 (0.6)
Inner city district
    No22 (75.9)535 (82.1)1 (–)
    Yes7 (24.1)117 (17.9)1.5 (0.64 to 3.5)0.35
Smoker
    No7 (24.1)296 (45.4)1 (–)
    Yes22 (75.9)341 (52.3)2.6 (1.1 to 6.2)0.025
    Unknown0 (0)15 (2.3)
Alcoholic
    No16 (55.2)469 (71.9)1 (–)
    Yes13 (44.8)169 (25.9)2.4 (1.1 to 4.9)0.022
    Unknown0 (0)14 (2.1)
Homeless
    No27 (93.1)610 (93.6)1 (–)
    Yes2 (6.9)39 (6)1.21 (0.29 to 5.1)0.8
Prison
    No23 (79.3)604 (92.6)1 (–)
    Yes6 (20.7)47 (7.2)3.5 (1.4 to 8.6)0.006
    Unknown0 (0)1 (0.2)
Mixed TB
    No22 (75.9)598 (91.7)1 (–)
    Yes7 (24.1)54 (8.3)3.2 (1.3 to 7.9)0.01
Smear test
    Negative10 (34.5)357 (54.8)1 (–)
    Positive19 (65.5)295 (45.2)1.5 (0.7 to 3.2)0.29
Resistance
    No28 (96.6)603 (92.5)– (–)
    Primary0 (0)30 (4.6)
    Secondary1 (3.4)11 (1.7)
    Unknown0 (0)8 (1.2)
MDR TB
    Yes0 (0)7 (1.1)– (–)
    No0 (0)641 (98.3)
    Unknown0 (0)4 (0.6)
  • HIV, human immunodeficiency virus; IDU, intravenous drug user; IQR, interquartile range; MDR TB, multidrug-resistant tuberculosis.