Table 3 Predictors of initiation, first break of at least 90 days and re-initiation after a break of beta-blocker treatment among patients aged 30–64 years and 65–74 years who survived a first hospitalisation for acute myocardial infarction in the period 1995–2001

	Beta-blockers
	Initiation		First break		Re-initiation
	Model 1	Model 2	Model 1	Model 2	Model 1	Model 2
	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)	HR (95% CI)
Age 30–64 years
Income
High	1.14 (1.09–1.18)	1.12 (1.08–1.17)	1.04 (0.97–1.11)	1.02 (0.96–1.10)	0.89 (0.80–0.99)	0.91 (0.82–1.02)
Medium	1.07 (1.02–1.11)	1.06 (1.02–1.10)	1.01 (0.95–1.08)	1.01 (0.95–1.08)	0.98 (0.88–1.08)	0.99 (0.89–1.09)
Low∗	1	1	1	1	1	1
p value^†	<0.0001	<0.0001	0.48	0.79	0.06	0.20
Education
High	1.08 (1.03–1.14)	1.04 (0.99–1.09)	1.09 (1.01–1.17)	1.08 (0.99–1.17)	0.89 (0.78–1.00)	0.92 (0.81–1.05)
Medium	1.04 (1.01–1.08)	1.02 (0.99–1.06)	0.98 (0.93–1.03)	0.97 (0.92–1.03)	0.92 (0.84–1.01)	0.93 (0.85–1.02)
Low∗	1	1	1	1	1	1
p value^†	0.002	0.24	0.02	0.03	0.07	0.25
Age 65–74 years
Income
High	1.18 (1.12–1.24)	1.19 (1.12–1.25)	1.12 (1.03–1.23)	1.11 (1.01–1.22)	0.94 (0.81–1.08)	0.95 (0.82–1.11)
Medium	1.07 (1.01–1.12)	1.07 (1.02–1.13)	1.02 (0.93–1.11)	1.01 (0.93–1.11)	1.05 (0.91–1.21)	1.05 (0.91–1.21)
Low∗	1	1	1	1	1	1
p value^†	<0.0001	<0.0001	0.02	0.05	0.28	0.42
Education
High	1.06 (0.98–1.13)	0.98 (0.91–1.06)	1.10 (0.98–1.23)	1.05 (0.93–1.18)	0.86 (0.70–1.05)	0.88 (0.72–1.09)
Medium	0.99 (0.94–1.03)	0.96 (0.92–1.01)	1.05 (0.97–1.13)	1.03 (0.95–1.12)	1.05 (0.93–1.20)	1.06 (0.93–1.21)
Low∗	1	1	1	1	1	1
p value^†	0.20	0.25	0.23	0.68	0.15	0.21

Model 1: Effects of income and education are estimated separately with adjustment for baseline characteristics.
Model 2: Effects of income and education are estimated simultaneously with adjustment for baseline characteristics.
∗Reference
^†Test that all categories within variable are equal.