Indicators of diagnostic validity and 95% confidence intervals (CI) of self reported prevalent cancer by tumour site. EPIC-Spain cohort (n = 41238)
| n (%)* | True positives | False negatives | False positives | Sensitivity | (CI) | Specificity | (CI) | VPP | (CI) | VPN | (CI) | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| *Number of confirmed cases and percentage of the total. False negatives = another site reported + cancer not reported (in parentheses the number not reporting cancer). False positives = another site confirmed + cancer not confirmed (in parentheses the number with non-confirmed cancer). | ||||||||||||
| Breast | 84 (26.3) | 71 | 13 (9) | 15 (13) | 84.5 | (75.0 to 91.5) | 100.0 | (99.9 to 100.0) | 82.6 | (72.9 to 89.9) | 100.0 | (100.0 to 100.0) |
| Oral cavity | 17 (5.3) | 4 | 13 (9) | 6 (3) | 23.5 | (6.8 to 49.9) | 100.0 | (100.0 to 100.0) | 40.0 | (12.2 to 73.8) | 100.0 | (100.0 to 100.0) |
| Stomach | 12 (3.8) | 6 | 6 (3) | 0 | 50.0 | (21.1 to 78.9) | 100.0 | (100.0 to 100.0) | 100.0 | (54.1 to 100.0) | 100.0 | (100.0 to 100.0) |
| Colorectal | 23 (7.2) | 4 | 19 (18) | 1 (1) | 17.4 | (5.0 to 38.8) | 100.0 | (100.0 to 100.0) | 80.0 | (28.4 to 99.5) | 100.0 | (99.9 to 100.0) |
| Uteri SAI | 74 (23.1) | 23 | 51 (46) | 32 (27) | 31.1 | (20.8 to 42.9) | 99.9 | (99.9 to 100.0) | 41.8 | (28.7 to 55.9) | 99.9 | (99.8 to 99.9) |
| Cervix uteri | 53 (16.6) | 7 | 46 (33) | 7 (5) | 13.2 | (5.5 to 25.3) | 100.0 | (100.0 to 100.0) | 50.0 | (23.0 to 77.0) | 99.9 | (99.9 to 99.9) |
| Corpus uteri | 20 (6.3) | 3 | 17 (13) | 5 (5) | 15.0 | (3.2 to 37.9) | 100.0 | (100.0 to 100.0) | 37.5 | (8.5 to 75.5) | 100.0 | (99.9 to 100.0) |
| Bladder | 23 (7.2) | 5 | 18 (17) | 0 | 21.7 | (7.5 to 43.7) | 100.0 | (100.0 to 100.0) | 100.0 | (47.8 to 100.0) | 100.0 | (99.9 to 100.0) |
| Thyroid | 21 (6.6) | 13 | 8 (8) | 2 (2) | 61.9 | (38.4 to 81.9) | 100.0 | (100.0 to 100.0) | 86.7 | (59.5 to 98.3) | 100.0 | (100.0 to 100.0) |
| Lung | 8 (2.5) | 4 | 4 (3) | 3 (2) | 50.0 | (15.7 to 84.3) | 100.0 | (100.0 to 100.0) | 57.1 | (18.4 to 90.1) | 100.0 | (100.0 to 100.0) |