Table 1

 Hazard ratios for death from ischaemic heart disease, cerebrovascular disease, and occlusive stroke (95% CI) in 11474 men and women born 1915–1929. Adjusted for age, period of birth, sex, and social characteristics (mother’s civil status and social group when the study subject was born, and subject’s own social group, education, marital status, and household car ownership from 1960 census)

Ischaemic heart diseaseCerebrovascular diseaseCerebrovascular disease: occlusive stroke
Number of eventsHR (95% CI) age, period, and sex adjustedHR (95% CI) fully adjustedNumber of eventsHR (95% CI) age, period, and sex adjustedHR (95% CI) fully adjustedNumber of eventsHR (95% CI) age, period, and sex adjustedHR (95% CI) fully adjusted
Total number of events 1960–20011211355127
Weight for gestational age (quintiles)
Lowest2591.01.0681.01.0221.01.0
2nd2420.83 (0.70,0.99)0.84 (0.71,1.00)841.06 (0.77,1.45)1.08 (0.78,1.49)291.09 (0.63,1.90)1.12 (0.64,1.96)
3rd2600.87 (0.73,1.03)0.92 (0.77,1.09)750.91 (0.66,1.27)0.95 (0.68,1.32)301.09 (0.63,1.90)1.16 (0.66,2.01)
4th2180.74 (0.62,0.89)0.77 (0.65,0.93)690.83 (0.60,1.17)0.87 (0.62,1.21)220.80 (0.44,1.45)0.86 (0.47,1.55)
Highest2320.76 (0.63,0.90)0.80 (0.67,0.96)590.70 (0.50,1.00)0.74 (0.52,1.05)240.82 (0.46,1.48)0.89 (0.50,1.61)
p value heterog 4 df0.0070.0350.1360.2250.6730.764
p value linear trend0.0010.0100.0150.0350.2660.421
Gestational age (weeks)
30–35521.01.0231.01.0151.01.0
36–371080.92 (0.66,1.28)0.95 (0.68,1.32)390.72 (0.43,1.20)0.74 (0.44,1.25)130.37 (0.18,0.78)0.39 (0.18,0.82)
38–393950.94 (0.70,1.26)1.01 (0.75,1.35)1220.62 (0.40,0.97)0.66 (0.42,1.03)370.29 (0.16,0.53)0.32 (0.17,0.58)
40–415091.01 (0.76,1.35)1.08 (0.81,1.44)1330.56 (0.36,0.88)0.60 (0.38,0.94)500.32 (0.18,0.58)0.36 (0.20,0.65)
42+1471.06 (0.77,1.45)1.09 (0.80,1.50)380.57 (0.34,0.96)0.60 (0.35,0.99)120.28 (0.13,0.59)0.29 (0.14,0.63)
p value heterog 4 df0.6630.7750.1480.2340.0070.015
p value linear trend0.2270.1600.0210.0310.0090.016