Prevalence of CHD and means and prevalences of other characteristics across thirds of birth weight
| Birth weight third (range kg) | p linear trend across thirds | |||
|---|---|---|---|---|
| Lowest (1.50 to 3.06) | Middle (3.07 to 3.64) | Highest (3.65 to 4.57) | ||
| n = 477 | n = 532 | n = 385 | ||
| *Doctor diagnosis of diabetes and/or fasting glucose concentration ≥7.8 mmol/l; †geometric means. CHD, coronary heart disease; HOMA, homeostasis model assessment (assessed in non-diabetics only; HDLC, high density lipoprotein cholesterol. | ||||
| Age (y) | 67.3 (66.8 to 67.8) | 68.0 (67.5 to 68.5) | 68.3 (67.7 to 68.8) | 0.006 |
| CHD (%) | 17.4 (14.2 to 21.1) | 13.9 (11.3 to 16.8) | 12.1 (9.2 to 15.9) | 0.01 |
| Adult anthropometric measures | ||||
| Weight (kg) | 68.9 (67.7 to 70.1) | 70.3 (69.2 to 71.5) | 72.4 (70.9 to 73.8) | <0.001 |
| Height (m) | 1.58 (1.57 to 1.59) | 1.60 (1.59 to 1.61) | 1.62 (1.61 to 1.63) | <0.001 |
| Body mass index (kg/m2) | 27.5 (27.1 to 28.0) | 27.7 (27.2 to 28.1) | 27.9 (27.2 to 28.3) | 0.55 |
| Waist to hip ratio | 0.823 (0.817 to 0.830) | 0.817 (0.810 to 0.823) | 0.817 (0.809 to 0.824) | 0.15 |
| Potential mediating factors (components of the insulin resistance syndrome and menopausal age) | ||||
| Diabetes (%)* | 7.5 (5.4 to 10.3) | 5.5 (3.8 to 10.3) | 6.8 (4.6 to 9.8) | 0.62 |
| HOMA score† | 1.76 (1.64 to 1.88) | 1.68 (1.59 to 1.79) | 1.44 (1.34 to 1.55) | 0.001 |
| Systolic BP (mm Hg) | 144.8 (142.6 to 147.1) | 146.5 (144.3 to 148.7) | 144.0 (141.5 to 146.7) | 0.74 |
| Diastolic BP (mm Hg) | 78.8 (77.7 to 79.9) | 79.1 (78.1 to 80.1) | 78.2 (77.0 to 79.4) | 0.55 |
| HDLc (mmol/l) | 1.66 (1.62 to 1.70) | 1.67 (1.63 to 1.72) | 1.67 (1.62 to 1.72) | 0.76 |
| Triglyceride values (mmol/l)† | 1.72 (1.64 to 1.79) | 1.68 (1.61 to 1.76) | 1.64 (1.55 to 1.72) | 0.19 |
| Age menopause (y) | 49.7 (48.2 to 50.2) | 49.3 (48.8 to 49.9) | 49.4 (48.9 to 49.9) | 0.40 |
| Potential confounding factors (indicators of childhood and adult socioeconomic position and smoking) | ||||
| Childhood manual social class (%) | 77.9 (73.8 to 81.5) | 75.5 (71.8 to 79.0) | 73.6 (69.1 to 77.8) | 0.07 |
| No bathroom in house as a child (%) | 38.4 (34.1 to 42.8) | 33.0 (28.5 to 37.8) | 31.2 (27.4 to 35.3) | 0.06 |
| No hot water in house as a child (%) | 33.3 (29.2 to 37.7) | 32.2 (27.7 to 37.0) | 25.4 (21.9 to 29.2) | 0.03 |
| No family access to car as a child (%) | 77.8 (73.8 to 81.3) | 75.6 (71.7 to 79.0) | 77.9 (73.5 to 81.8) | 0.97 |
| Left full time education younger than 15 years (%) | 25.6 (21.9 to 30.0) | 25.2 (21.7 to 29.0) | 31.4 (27.0 to 36.2) | 0.07 |
| Adult manual social class (%) | 48.2 (43.6 to 52.8) | 45.0 (40.7 to 49.4) | 42.7 (37.6 to 47.7) | 0.05 |
| No car access as adult (%) | 23.6 (20.0 to 27.6) | 22.6 (19.2 to 26.3) | 22.7 (18.9 to 27.0) | 0.74 |
| Living in local authority housing (%) | 9.6 (7.3 to 12.6) | 8.8 (6.7 to 11.6) | 10.9 (8.2 to 14.4) | 0.57 |
| No private or work pension (%) | 22.2 (18.7 to 26.2) | 24.4 (21.0 to 28.3) | 22.6 (18.7 to 27.0) | 0.85 |
| Ever smoker (%) | 50.0 (45.5 to 54.5) | 43.8 (39.6 to 48.0) | 50.6 (45.7 to 55.6) | 0.97 |