Cox regression coefficients and 95% confidence intervals (95% CI) for the risk factors included in the Framingham functions for 10 year incidence of coronary deaths and recognised non-fatal myocardial infarction (hard end points) by sex
| Risk factors (units) | Risk factor categories | Men Cox regression coefficient estimates (95% CI) | Women Cox regression coefficient estimates (95% CI) |
|---|---|---|---|
| S, systolic blood pressure; D, diastolic blood pressure; HDL, high density lipoprotein. | |||
| *Risk factor means refers to the mean age and to the proportion of population in each level of the risk factors. | |||
| Age (y) | Mean | 0.05 (0.04 to 0.07) | 0.17 (−0.03 to 0.37) |
| Age (y) squared | Mean squared | – | −0.001 (0.003 to 0.001) |
| Total cholesterol (mg/dl) | <160 | −0.38 (−1.18 to 0.42) | −0.21 (−1.73 to 1.32) |
| 160–199 | 0.00 | 0.00 | |
| 200–239 | 0.57 (0.22 to 0.92) | 0.44 (−0.21 to 1.09) | |
| 240–279 | 0.74 (0.36 to 1.13) | 0.56 (−0.11 to 1.22) | |
| ⩾280 | 0.83 (0.33 to 1.32) | 0.89 (0.19 to 1.80) | |
| HDL-cholesterol (mg/dl) | <35 | 0.61 (0.16 to 1.06) | 0.73 (0.00 to 1.46) |
| 35–44 | 0.37 (−0.06 to 0.79) | 0.60 (0.05 to 1.15) | |
| 45–49 | 0.00 | 0.60 (0.05 to 1.14) | |
| 50–59 | 0.00 (−0.47 to 0.47) | 0.00 | |
| >59 | −0.46 (−1.09 to 0.17) | −0.54 (−1.10 to 0.02) | |
| Blood pressure (mm Hg) | Optimal (S<120)/(D<80) | 0.09 (−0.41 to 0.60) | −0.74 (−1.53 to 0.05) |
| Normal (S 120–129)/(D 80–84) | 0.00 | 0.00 | |
| High normal (S 130–139)/(D 85–89) | 0.42 (−0.02 to 0.86) | –0.37 (–1.09 to 0.35) | |
| Stage I (S 140–159)/(D90–99) | 0.66 (0.25 to 1.07) | 0.22 (−0.38 to 0.81) | |
| Stage II–IV (S⩾160)/(D⩾100) | 0.90 (0.46 to 1.33) | 0.61 (0.00 to 1.21) | |
| Diabetes | 0.53 (0.11 to 0.94) | 0.87 (0.33 to 1.40) | |
| Smoking | Current 1 cigarette/day consumption | 0.73 (0.47 to 0.98) | 0.98 (0.57 to 1.38) |