Table 1

	β blockers⁷	ACE inhibitors⁸	Spironolactone⁹
Using trial data for baseline risk. Comparison of impact of β blockers, ACE inhibitors, and spironolactone on one year all cause mortality for congestive heart failure. NNT is the reciprocal of the absolute risk reduction. P_e is the proportion of the population with disease eligible for the intervention. P_d is the proportion of the population with the disease. Baseline risk is derived from the outcome rate in the placebo group of the particular trial.^7–⁹ PIN has been rounded to the nearest 100
Baseline risk	0.11	0.115	0.23
Relative risk reduction	0.34	0.16	0.30
Absolute risk reduction	0.0374	0.0184	0.069
NNT	26.7	54.3	14.5
P_e	0.75	0.75	0.73
Disease impact number (DIN)	35.7	72.5	19.9
P_d	0.0042	0.0042	0.0042
Population impact number (PIN)	8500	17300	4700