Fibrinogen and risk of stroke*
| Quartile II | Quartile III | Quartile IV | Trend† | |
|---|---|---|---|---|
| *Odds ratios relative to subjects with a fibrinogen in the first quartile of the centre specific distribution with 95% confidence intervals; †odds ratio per quartile increase based on the centre specific distribution, adjusted for age, sex, smoking, systolic blood pressure; ‡including unspecified strokes. | ||||
| All strokes | 1.08 (0.63 to 1.84) | 1.91 (1.12 to 3.26) | 2.78 (1.64 to 4.72) | 1.47 (1.24 to 1.73) |
| First ever | 1.09 (0.62 to 1.91) | 1.91 (1.10 to 3.34) | 2.52 (1.45 to 4.41) | 1.41 (1.19 to 1.68) |
| Fatal | 0.57 (0.21 to 1.55) | 1.16 (0.45 to 2.99) | 2.30 (0.96 to 5.57) | 1.47 (1.08 to 1.98) |
| Non-fatal | 1.30 (0.71 to 2.9) | 2.29 (1.25 to 4.19) | 2.98 (1.64 to 5.43) | 1.48 (1.23 to 1.77) |
| Haemorrhagic | 2.17 (0.41 to 11.5) | 6.76 (0.94 to 32.4) | 6.59 (1.31 to 33.3) | 1.85 (1.22 to 2.81) |
| Ischaemic | 0.91 (0.50 to 1.65) | 1.44 (0.79 to 2.62) | 2.25 (1.26 to 4.02) | 1.37 (1.14 to 1.65) |
| Ischaemic‡ | 0.99 (0.57 to 1.73) | 1.64 (0.94 to 2.88) | 2.54 (1.47 to 4.39) | 1.42 (1.20 to 1.69) |