Characteristics of HIV infected IDUs according to prescription of HAART (enrolment and last follow up visits in the French MANIF 2000 cohort study) (n=188)
| At enrolment | At last follow up | |||||
|---|---|---|---|---|---|---|
| Was prescribed HAART during follow up | HAART treatment | |||||
| No (n=154) | Yes (n=34) | p | No (n=154) | Yes (n=34) | p | |
| *Metropolitan area = more than 1 million inhabitants; medium size town = more than 300000 inhabitants; small towns = more than 100000 inhabitants; †patients with possible depression (score >17 in the French version of CES-D administered at visit11, 12); ‡during the 6 months prior to the visit. No difference of date between the two groups (Mann-Whitney p=0.846). (1) Mann Whitney test. (2) χ2test or exact test of Fisher. | ||||||
| mean (SD) | mean (SD) | (1) | mean (SD) | mean (SD) | (1) | |
| CD4 cell counts/mm3 | 550 (230) | 430 (180) | <0.001 | 520 (210) | 510 (270) | NS |
| Log10 plasma viral load | 3.99 (1.0) | 4.72 (0.9) | <0.001 | 3.50 (0.9) | 3.31 (1.1) | NS |
| Age | 33 (4.3) | 33 (5.1) | NS | – | – | – |
| Time of follow up in the medical department before enrolment (years) | 4.4 (2.8) | 3.6 (3.2) | NS | – | – | – |
| % | % | (2) | % | % | (2) | |
| Place of residence* | ||||||
| Metropolitan areas | 53.2 | 55.9 | – | – | ||
| Medium size towns | 38.3 | 41.2 | NS | – | – | – |
| Small towns and rural areas | 8.4 | 2.9 | – | – | ||
| Male gender | 68.2 | 64.7 | NS | – | – | – |
| Employed | 29.9 | 29.4 | NS | – | – | – |
| Level of education ≥ high school certificate | 24.0 | 23.5 | NS | – | – | – |
| Homeless | 4.5 | 2.9 | NS | – | – | – |
| Time after enrollment for last follow up visit in the cohort | ||||||
| 6 months | – | – | 12.3 | 14.7 | ||
| 12 months | – | – | – | 27.3 | 29.4 | NS |
| 18 months | – | – | 60.4 | 55.9 | ||
| Undetectable viral load | 11.7 | 5.9 | NS | 20.8 | 41.2 | <0.05 |
| Depressed† | 55.8 | 64.7 | NS | 46.8 | 52.9 | NS |
| Alcohol consumption ≥5 glasses/day‡ | 17.8 | 15.4 | NS | 13.0 | 2.9 | NS |
| In drug maintenance treatment (DMT)‡ | 37.0 | 26.5 | NS | 38.3 | 26.5 | NS |
| Injected drugs‡ | 49.4 | 44.1 | NS | 20.8 | 14.7 | NS |
| Shared cooker, cotton or water for injecting‡ | 19.5 | 29.5 | NS | 5.8 | 5.9 | NS |
| Had sexual intercourse with‡ | ||||||
| No partner | – | – | 13.6 | 17.6 | ||
| Main partner only | 45.5 | 41.2 | NS | 44.2 | 47.1 | NS |
| Main and occasional partners | 9.7 | 11.8 | 9.7 | 5.9 | ||
| Occasional partners only | 44.8 | 47.1 | 32.5 | 29.4 | ||
| HIV positive main sexual partner‡ | 20.1 | 14.7 | NS | 22.7 | 17.6 | NS |
| Had at least one episode of‡ : | ||||||
| oral sex | 83.1 | 79.4 | NS | 57.8 | 55.9 | NS |
| anal intercourse | 31.2 | 47.1 | NS | 24.0 | 29.4 | NS |
| Had at least one episode of unprotected sex‡ | 43.5 | 47.1 | NS | 35.7 | 23.5 | NS |