Sociodemographic characteristics, cardiac risk factors, and indicators of initial disease severity in male and female responders
| Men (n=382) | Women (n=337) | p Value | |||||
|---|---|---|---|---|---|---|---|
| *Family history refers to first degree relatives. †Creatinine kinase only measured in patients whose working diagnosis was AMI. The CK iso-enzyme CK-MB should be used, but it was only measured at follow up in 156 (21.7%) patients, so the CPK was used in the analysis instead. | |||||||
| Sociodemographic characteristics | |||||||
| Mean age (ys) | 60.7 | 64.0 | <0.001 | ||||
| White | 362 | (94.8) | 324 | (96.1) | 0.38 | ||
| Carstairs mean deprivation score | −0.13 | n=352 | −0.24 | n=300 | 0.59 | ||
| Regular smoker | 136 | (43.9) | 91 | (42.9) | 0.83 | ||
| Alcohol (ever) | 353 | (96.2) | 259 | (81.2) | <0.001 | ||
| Family history* | |||||||
| Hypertension | 98 | (26.9) | n=364 | 120 | (39.5) | n=306 | 0.003 |
| Coronary artery disease | 221 | (60.2) | n=382 | 216 | (69.7) | n=337 | 0.01 |
| Hypercholesterolaemia | 39 | (10.7) | n=365 | 42 | (13.8) | n=305 | 0.33 |
| Past medical history | |||||||
| Diabetes | 30 | (8.2) | n=382 | 40 | (12.7) | n=337 | 0.05 |
| Hypertension | 104 | (28.6) | n=382 | 143 | (46.1) | n=337 | <0.001 |
| Angina | 154 | (42.7) | n=382 | 142 | (45.4) | n=337 | 0.48 |
| Acute myocardial infarction | 141 | (39.4) | n=382 | 91 | (29.2) | n=337 | 0.006 |
| Hypercholesterolaemia | 102 | (28.6) | n=382 | 85 | (28.6) | n=337 | 0.99 |
| Previous CABG | 30 | (8.2) | n=366 | 16 | (5.0) | n=317 | 0.10 |
| Previous PTCA | 29 | (7.9) | n=365 | 11 | (3.4) | n=319 | 0.01 |
| Previous angiogram | 46 | (12.0) | n=382 | 32 | (9.5) | n=337 | 0.27 |
| Indicators of disease severity | |||||||
| Q wave infarction | 157 | (70.4) | n=223 | 94 | (58.8) | n=160 | 0.02 |
| Clinical / radiological evidence of heart failure during admission | 81 | (21.4) | n=379 | 60 | (18.2) | n=329 | 0.30 |
| Abnormal CK† | 195 | (60.6) | n=322 | 131 | (48.3) | n=271 | 0.003 |
| Recurrence of signs / symptoms of ischaemia | 142 | (37.4) | n=380 | 135 | (41.4) | n=326 | 0.27 |
| If recurrent ischaemia, mean number of times (median, interquartile range) | 3.22 | (2.0, 1.0–3.0) | 3.60 | (2.0, 1.0–4.0) | 0.42 | ||
| Mean duration of pre-discharge exercise test (min) (median, interquartile range) | 7.34 | (8.0, 5.0–9.2) | (n=41) | 7.47 | (6.6, 4.4–10.2) | (n=39) | 0.81 |
| Discharge diagnosis | |||||||
| Acute myocardial infarction | 223 | (59.2) | n=377 | 160 | (48.8) | n=328 | 0.01 |
| Angina | 128 | (34.1) | n=375 | 143 | (43.3) | n=330 | 0.01 |
| Non-cardiac cause | 10 | (2.6) | n=378 | 10 | (3.1) | n=327 | 0.74 |
| Further investigation required | 14 | (3.7) | n=376 | 14 | (4.3) | n=328 | 0.71 |