Independent determinants of the prevalence of current injecting and the incidence of injecting transitions, using 13 620 visits of 996 drug users in the Amsterdam Cohort Study
Current injecting OR |
Initiation OR |
Cessation OR |
Relapse OR | |
Year3-151 | 1.17 | 0.573-150 | 0.71 | 0.803-150 |
Year3-150Year3-151 | 0.963-165 | — | 1.053-160 | — |
Female | 0.643-165 | — | — | — |
Non-West European ethnicity | 0.233-165 | 0.323-150 | 1.603-160 | — |
Non-Dutch nationality | 1.953-165 | — | — | — |
Age3-152 | — | 0.613-150 | — | 0.853-150 |
Duration of injecting3-152 | NA | NA | — | 1.143-150 |
HIV positive | 1.403-160 | — | — | — |
Duration stopped injecting3-152 | NA | NA | NA | 0.813-165 |
Current behaviours: 3-153 | ||||
Non-injecting heroin use3-154 | ||||
<daily | 0.97 | 3.48 | 1.343-165 | — |
daily | 0.803-160 | 7.133-160 | 1.683-165 | — |
Non-injecting cocaine use3-154 | ||||
<daily | 0.813-165 | — | — | — |
daily | 0.91 | — | — | — |
Tranquiliser use3-154 | ||||
<daily | 1.333-165 | 2.44 | — | 1.403-150 |
daily | 1.223-160 | 3.473-150 | — | 0.98 |
Prostitution | 1.633-165 | — | — | — |
Steady sexual partner | ||||
none | 1 | 1 | 1 | 1 |
currently injecting | 1.563-165 | 3.353-150 | 0.703-160 | 1.17 |
stopped injecting | 0.583-165 | 2.40 | 1.22 | 0.87 |
never injected | 0.663-165 | 0.89 | 1.223-150 | 0.673-165 |
Daily methadone | 0.763-165 | — | — | — |
AIDS diagnosis | — | — | 1.803-160 | — |
Needles via exchange | ||||
none | NA | NA | 1 | NA |
1–99% | 0.673-160 | |||
100% | 0.503-165 | |||
Frequency injecting | ||||
<daily | NA | NA | 1 | NA |
daily | 0.473-165 | |||
>daily | 0.383-165 |
↵3-150 , p<0.05;
↵3-160 , p<0.01;
↵3-165 , p<0.001; GEE was used for significance testing, using a logistic link function; calendar year was forced into the models; NA, not applicable.
↵3-151 OR expressed per five year increase in calendar year.
↵3-152 OR expressed per category of years (see methods).
↵3-153 For injecting transitions, current behaviours were measured at the last cohort visit preceding the transition. For prevalence of current injecting, they were measured at the same visit as current injecting.
↵3-154 Reference group is no use of drug.