Table 4

Effect estimates (as odds ratios, with 95% CI and p value) from models of perception of a family weakness attributable to heart disease, based on all data and subgroups defined by gender, social class or prevalence of a parental CHD death

Effect	Subjects included
Effect	All	Sons	Daughters	Manual	Non-manual	No parental CHD deaths	⩾1 parental CHD death
Age^4-150	0.8	0.8	0.8	1.0	0.8	0.9	0.8
	(0.7, 1.0)	(0.6, 1.1)	(0.7, 1.1)	(0.7, 1.4)	(0.6, 0.9)	(0.7, 1.1)	(0.6, 1.0)
	0.03	0.2	0.1	0.96	0.01	0.2	0.06
Gender^4-151	1.6	—	—	2.0	1.4	1.5	1.6
	(1.2, 2.0)			(1.3, 3.0)	(1.1, 1.9)	(1.1, 2.1)	(1.1, 2.4)
	0.0004			0.003	0.02	0.01	0.01
Social class^4-152	0.8	0.7	0.9	—	—	0.9	0.7
	(0.6, 1.0)	0.4, 1.0)	(0.6, 1.3)			(0.6, 1.3)	(0.5, 1.0)
	0.09	0.04	0.6			0.5	0.07
One parental CHD death^4-153	3.2	3.1	3.1	2.3	3.6	—	—
	(2.5, 4.0)	(2.1, 4.7)	(2.3, 4.3)	(1.5, 3.7)	(2.7, 4.8)
	<0.0001	<0.0001	<0.0001	0.0003	<0.0001
Two parental CHD deaths	7.9	3.5	13.0	19.3	4.3	—	2.6^4-154
	(4.1, 15.2)	(1.1, 11.4)	(5.4, 31.4)	(6.4, 58.7)	(1.8, 10.3)		(1.3, 5.1)
	<0.0001	0.03	<0.0001	<0.0001	0.001		0.005

↵4-150 Age effect is for a 10 year difference in offspring age.
↵4-151 Gender effect is for daughters relative to sons.
↵4-152 Social class effect is for offspring in manual relative to non-manual occupations.
↵4-153 Parental CHD death effects (one or two deaths) are relative to offspring whose parents were either alive, or had died from a cause other than CHD.
↵4-154 Effect estimate for two parental CHD deaths is relative to one parental CHD death group.