Table 3

Factor loadings of tumor profiles. (A) Male loadings, (B) female loadings. The factor loadings are the correlation coefficients between original variables (in this case tumour sites relative percentages) and components, so they help in the elucidation of the meaning of components. In this particular case the components correspond to specific sets of tumours whose relative abundance is correlated at the level of populations

A	PCM1	PCM2	PCM3	PCM4	PCM5
Lip	−0.050	0.599	0.007	0.153	0.658
Tongue	−0.906	0.113	0.123	0.046	0.131
Saliv gland	0.254	−0.075	0.185	0.205	0.192
Mouth	−0.888	0.034	0.141	0.036	0.062
Oropharynx	−0.902	−0.145	0.172	0.044	−0.056
Nasopharynx	−0.224	0.740	−0.269	0.388	0.031
Hypopharynx	−0.917	−0.201	0.102	0.078	0.039
Pharynx unsp	−0.692	0.137	0.042	−0.092	0.217
Oesophagus	−0.660	−0.316	0.247	−0.362	0.051
Stomach	0.280	0.576	0.133	0.094	−0.117
Small intest	0.042	−0.538	−0.037	0.463	0.343
Colon	0.164	−0.590	−0.475	−0.175	−0.281
Rectum	−0.002	−0.253	0.209	−0.384	−0.146
Liver	−0.290	0.476	−0.363	0.454	−0.232
Gall bladder	0.265	0.539	−0.154	0.392	−0.277
Pancreas	0.748	0.091	0.423	0.020	−0.252
Nose, sinuses	−0.540	−0.270	0.181	0.517	0.001
Larynx	−0.439	0.763	−0.134	0.088	0.149
Lung	0.233	0.437	0.264	−0.558	−0.421
Other thorac	−0.035	0.353	0.280	0.090	−0.420
Bone	0.154	0.505	0.585	0.096	0.264
Conn tissue	0.408	0.023	0.453	0.034	0.369
Melanoma	0.482	−0.565	0.113	0.160	0.141
Breast	−0.159	−0.191	−0.213	0.367	−0.332
Prostate	−0.006	−0.790	0.013	0.344	0.310
Testis	0.131	−0.572	0.422	0.052	−0.203
Penis	0.079	0.254	−0.117	−0.090	0.377
Bladder	0.034	0.194	−0.765	0.067	0.214
Kidney	0.235	−0.097	0.261	0.644	−0.501
Eye	0.078	−0.214	0.732	0.015	0.330
Brain	0.538	0.288	0.041	0.270	0.177
Thyroid	0.144	−0.0196	0.010	0.796	0.001
Other endocrine	0.245	0.258	0.004	−0.076	−0.183
Hodgkin's d	0.270	0.410	0.443	0.154	0.035
non-H lym	0.262	−0.582	−0.496	0.078	0.094
Mult myel	0.640	−0.326	−0.477	−0.009	0.211
Lym leuk	0.337	0.258	0.210	−0.327	0.240
Myel leuk	0.516	−0.026	−0.263	−0.291	0.287
Oth leuk	−0.204	0.008	−0.200	−0.024	−0.067
Leuk unsp	0.300	−0.227	0.349	0.427	0.051
% exp var	18.8	16.1	9.9	8.7	6.5
B	PCF1	PCF2	PCF3	PCF4	PCF5
Lip	0.660	0.079	0.048	0.332	0.251
Tongue	−0.022	0.532	0.087	0.150	0.114
Saliv gland	0.457	0.233	−0.246	−0.316	0.008
Mouth	−0.171	0.331	0.185	−0.001	0.262
Oropharynx	−0.197	0.083	0.647	−0.186	−0.337
Nasopharynx	0.389	0.332	0.023	0.043	−0.057
Hypopharynx	−0.727	−0.025	0.226	0.107	−0.116
Pharynx unsp	−0.492	−0.274	−0.062	0.240	−0.118
Oesophagus	−0.647	−0.503	−0.253	0.176	0.135
Stomach	0.564	−0.061	−0.181	0.251	−0.097
Small intest	−0.215	0.307	0.230	−0.409	0.425
Colon	−0.588	0.387	0.000	0.069	0.010
Rectum	0.257	0.070	0.598	0.246	−0.094
Liver	0.684	0.357	−0.427	−0.162	−0.235
Gall bladder	0.732	0.189	−0.159	−0.408	−0.162
Pancreas	0.244	−0.244	−0.417	−0.383	0.431
Nose, sinuses	−0.213	−0.043	0.324	0.370	−0.002
Lung	−0.152	−0.423	−0.171	−0.264	−0.241
Other thorac	−0.476	−0.718	−0.382	−0.120	0.121
Bone	0.501	−0.142	−0.093	−0.421	−0.067
Conn tissue	0.763	−0.151	0.330	0.253	0.006
Melanoma	0.533	0.092	0.476	0.305	0.007
Breast	−0.380	0.193	0.443	−0.061	0.598
Uterus unsp	−0.567	0.547	0.287	0.164	−0.264
Cervix uteri	0.011	0.166	−0.479	0.022	−0.276
Placenta	0.517	−0.589	0.324	−0.234	−0.133
Corpus uteri	0.487	−0.241	0.254	−0.134	0.115
Ovary	0.788	0.247	0.326	−0.084	−0.039
Oth f gen	0.404	−0.644	0.308	−0.028	0.239
Bladder	0.424	0.166	−0.184	0.023	0.197
Kidney	−0.503	−0.012	−0.415	0.212	0.283
Eye	0.121	0.129	0.327	−0.780	0.158
Brain	0.414	−0.503	0.284	0.463	0.240
Thyroid	0.709	0.203	−0.302	−0.170	0.059
Oth endoc	0.120	0.670	0.188	−0.220	−0.036
Hodgkin's d	0.489	−0.199	−0.034	0.346	0.430
non-H lym	0.663	0.074	−0.130	0.227	−0.210
Mult myel	−0.472	0.699	0.003	0.059	0.122
Lym leuk	−0.219	0.526	−0.460	0.077	0.406
Myel leuk	0.517	0.123	−0.010	0.406	0.066
Oth leuk	0.278	0.197	−0.395	0.302	0.139
Leuk unsp	0.126	0.429	0.076	0.226	−0.041
% exp var	22.3	11.9	9.4	7.4	5.6

Hodgkin's dis = Hodgkin's disease; non-H lym = non-Hodgkin's lymphoma; Mult myel = multiple myeloma; Lym leuk = lymphoid leukaemia; Myel leuk = myeloid leukaemia; Oth leuk = other leukaemias; Leuk unsp = leukaemia unspecified.