ECG abnormalities: age adjusted prevalence and age adjusted hazard ratios2-150 (95% confidence intervals) for their effect on all cause and coronary mortality by symptomatic status
ECG abnormality (Minnesota code) | Asymptomatic (n=15 281)† | Symptomatic (n=2626)† | |||||
---|---|---|---|---|---|---|---|
% Prevalence of ECG abnormality (n) | All cause deaths (n=6381) | Coronary deaths (n=2023) | % Prevalence of ECG abnormality (n) | All cause deaths (n=1624) | Coronary deaths (n=721) | ||
Q and QS | |||||||
Large Q and QS (1:1) | 0.04 (6) | 2.56 (1.1, 6.2) | 1.56 (0.2, 11.1) | 0.7 (23) | 2.88 (1.9, 4.4) | 3.05 (1.7, 5.0) | |
Intermediate (1:2) | 0.4 (53) | 1.48 (1.0, 2.1) | 1.89 (1.1, 3.3) | 1.5 (46) | 1.44 (1.0, 2.0) | 2.13 (1.4, 3.2) | |
Small (1:3) | 1.2 (187) | 1.25 (1.0, 1.5) | 1.38 (1.0, 2.0) | 2.0 (59) | 1.62 (1.2, 2.1) | 2.43 (1.7, 3.4) | |
Left axis deviation (2:1) | 2.9 (440) | 1.13 (1.0, 1.3) | 1.17 (0.9, 1.5) | 4.4 (123) | 1.16 (0.9, 1.4) | 1.29 (0.9, 1.8) | |
Tall R wave amplitude (3:1) | 0.7 (101) | 0.98 (0.7, 1.3) | 0.95 (0.5, 1.6) | 0.9 (26) | 1.77 (1.2, 2.7) | 1.70 (0.9, 3.3) | |
S-T depression horizontal or downward sloping | |||||||
⩾0.5 mm and <1 mm (4:2 + 4:3) | 0.8 (115) | 1.80 (1.4, 2.2) | 2.26 (1.6, 3.2) | 4.0 (119) | 2.08 (1.7, 2.5) | 2.60 (2.0, 3.4) | |
⩾1 mm (4:1) | 0.1 (15) | 1.89 (0.9, 3.8) | 2.89 (1.1, 7.7) | 0.6 (16) | 4.54 (2.7, 7.6) | 5.68 (2.9, 11.1) | |
upwards sloping (4:4) | 0.1 (12) | 0.91 (0.3, 2.4) | 0.72 (0.1, 5.1) | 0.3 (6) | 1.48 (0.6, 3.6) | 1.36 (0.3, 5.5) | |
T inversion | |||||||
zero, negative or diphasic (5:3) | 3.0 (437) | 1.42 (1.3, 1.6) | 1.70 (1.4, 2.1) | 5.9 (175) | 1.77 (1.5, 2.1) | 2.27 (1.8, 2.9) | |
negative ⩾1 mm (5:1 + 5:2) | 0.6 (88) | 1.73 (1.3, 2.2) | 2.20 (1.5, 3.3) | 3.8 (114) | 2.29 (1.9, 2.8) | 3.15 (2.4, 4.1) | |
PR interval | |||||||
⩾0.22s (6:3) | 2.4 (364) | 0.95 (0.8, 1.1) | 1.11 (0.9, 1.4) | 3.1 (86) | 1.10 (0.9, 1.4) | 1.14 (0.8, 1.7) | |
<0.12s (6:5) | 0.6 (66) | 1.49 (1.1, 2.1) | 0.89 (0.4, 1.9) | 1.0 (10) | 0.89 (0.4, 1.9) | 0.95 (0.3, 2.9) | |
Ventricular conduction defect | |||||||
left bundle branch block (7:1) | 0.4 (54) | 1.35 (1.0, 1.9) | 1.67 (1.0, 2.9) | 1.6 (47) | 2.86 (2.1, 3.9) | 3.52 (2.3, 5.3) | |
right bundle branch block (7:2) | 1.1 (163) | 1.07 (0.9, 1.3) | 1.08 (0.7, 1.6) | 1.0 (28) | 1.41 (0.9, 2.2) | 1.25 (0.6, 2.4) | |
intraventricular block (7:4) | 0.6 (96) | 1.00 (0.7, 1.4) | 1.19 (0.7, 1.9) | 1.0 (32) | 1.88 (1.3, 2.8) | 1.79 (1.0, 3.2) | |
Arrhythmias | |||||||
frequent ectopics (8:1) | 1.4 (204) | 1.17 (1.0, 1.4) | 1.32 (1.0, 1.8) | 2.0 (59) | 1.43 (1.1, 1.9) | 1.34 (0.9, 2.1) | |
atrial fibrillation (8:3) | 0.2 (30) | 1.95 (1.3, 2.9) | 3.22 (1.8, 5.7) | 1.4 (45) | 1.86 (1.3, 2.6) | 1.18 (0.6, 2.2) | |
sinus tachycardia (>100/min) (8:7) | 2.4 (366) | 1.30 (1.1, 1.5) | 1.39 (1.1, 1.8) | 2.1 (54) | 1.83 (1.3, 2.5) | 2.20 (1.4, 3.4) | |
sinus bradycardia (<50/min) (8:8) | 1.3 (201) | 0.78 (0.6, 1.0) | 0.69 (0.4, 1.1) | 1.2 (33) | 1.08 (0.7, 1.7) | 0.98 (0.5, 2.0) | |
Low QRS amplitude (9:1) | 0.4 (60) | 1.12 (0.8, 1.6) | 0.50 (0.2, 1.3) | 0.5 (13) | 1.26 (0.7, 2.3) | 1.10 (0.4, 3.0) |
↵2-150 All hazard ratios are compared with the absence of the specific ECG abnormality. †Numbers of men and deaths in the analyses will be slightly fewer because of differing numbers of missing values for each specific ECG abnormality.