@article {Porrujech-2022-219487, author = {Fabio Porru and Merel Schuring and Witte J G Hoogendijk and Alex Burdorf and Suzan J W Robroek}, title = {Impact of mental disorders during education on work participation: a register-based longitudinal study on young adults with 10 years follow-up}, elocation-id = {jech-2022-219487}, year = {2023}, doi = {10.1136/jech-2022-219487}, publisher = {BMJ Publishing Group Ltd}, abstract = {Background Mental disorders are a leading cause of disability and a major threat to work participation in young adults. This register-based longitudinal study aims to investigate the influence of mental disorders on entering and exiting paid employment among young graduates and to explore differences across socioeconomic groups.Methods Register information on sociodemographics (age, sex, migration background) and employment status of 2 346 393 young adults who graduated from secondary vocational (n=1 004 395) and higher vocational education or university (n=1 341 998) in the period 2010{\textendash}2019 was provided by Statistics Netherlands. This information was enriched with register information on the prescription of nervous system medication for mental disorders in the year before graduation as a proxy for having a mental disorder. Cox proportional hazards regression models were used to estimate the influence of mental disorders on (A) entering paid employment among all graduates and (B) exiting from paid employment among graduates who had entered paid employment.Results Individuals with mental disorders were less likely to enter (HR 0.69{\textendash}0.70) and more likely to exit paid employment (HR 1.41{\textendash}1.42). Individuals using antipsychotics were the least likely to enter (HR 0.44) and the most likely to exit paid employment (HR 1.82{\textendash}1.91), followed by those using hypnotics and sedatives. The association between mental disorders and work participation was found across socioeconomic subgroups (ie, educational level, sex and migration background).Discussion Young adults with mental disorders are less likely to enter and maintain paid employment. These results ask for prevention of mental disorders and for a more inclusive labour market.Data may be obtained from a third party and are not publicly available.}, issn = {0143-005X}, URL = {https://jech.bmj.com/content/early/2023/05/16/jech-2022-219487}, eprint = {https://jech.bmj.com/content/early/2023/05/16/jech-2022-219487.full.pdf}, journal = {Journal of Epidemiology \& Community Health} }