TY - JOUR T1 - Clinical gynaecological perspectives to improve validity in clinical research: comment on the article by Chiuve <em>et al</em> JF - Journal of Epidemiology and Community Health JO - J Epidemiol Community Health DO - 10.1136/jech-2021-218426 SP - jech-2021-218426 AU - Shiho Oide AU - Ryo Okubo AU - Toshiharu Mitsuhashi AU - Kota Fukai AU - Hiroki Masuda AU - Yoshie Yamada AU - Takashi Yoshioka Y1 - 2022/03/03 UR - http://jech.bmj.com/content/early/2022/03/03/jech-2021-218426.abstract N2 - We read the article by Chiuve et al with great interest. We appreciate the authors’ novel and interesting study using large US nationwide healthcare insurance data to determine the rate of mental health diagnosis in women with uterine fibroids (UF), a topic that has never been studied.1 However, for future clinical research, we have two suggestions regarding its external validity and internal validity from clinical gynaecological perspectives.Our first concern is regarding its external validity. What clinical settings should gynaecologists extrapolate the results of this study to, for patients diagnosed with UF? … ER -