RT Journal Article
SR Electronic
T1 Effectiveness of a motivational intervention based on spirometry results to achieve smoking cessation in primary healthcare patients: randomised, parallel, controlled multicentre study
JF Journal of Epidemiology and Community Health
JO J Epidemiol Community Health
FD BMJ Publishing Group Ltd
SP 1001
OP 1009
DO 10.1136/jech-2020-216219
VO 75
IS 10
A1 Francisco Martin-Lujan
A1 Josep Basora-Gallisa
A1 Felipe Villalobos
A1 Nuria Martin-Vergara
A1 Estefania Aparicio-Llopis
A1 Irene Pascual-Palacios
A1 Antoni Santigosa-Ayala
A1 Roxana-Elena Catalin
A1 Cristina Rey-Reñones
A1 Rosa Solà
A1 ,
YR 2021
UL http://jech.bmj.com/content/75/10/1001.abstract
AB Objective This 12-month study in a primary healthcare network aimed to assess the effectiveness of usual smoking cessation advice compared with personalised information about the spirometry results.Design Randomised, parallel, controlled, multicentre clinical trial.Setting This study involved 12 primary healthcare centres (Tarragona, Spain).Participants Active smokers aged 35–70 years, without known respiratory disease. Each participant received brief smoking cessation advice along with a spirometry assessment. Participants with normal results were randomised to the intervention group (IG), including detailed spirometry information at baseline and 6-month follow-up or control group (CG), which was simply informed that their spirometry values were within normal parameters.Main outcome Prolonged abstinence (12 months) validated by expired-CO testing.Results Spirometry was normal in 571 patients in 571 patients (45.9% male), 286 allocated to IG and 285 to CG. Baseline characteristics were comparable between the groups. Mean age was 49.8 (SD ±7.78) years and mean cumulative smoking exposure was 29.2 (±18.7) pack-years. Prolonged abstinence was 5.6% (16/286) in the IG, compared with 2.1% (6/285) in the CG (p=0.03); the cumulative abstinence curve was favourable in the IG (HR 1.98; 95% CI 1.29 to 3.04).Conclusions In active smokers without known respiratory disease, brief advice plus detailed spirometry information doubled prolonged abstinence rates, compared with brief advice alone, in 12-month follow-up, suggesting a more effective intervention to achieve smoking cessation in primary healthcare.Trial registration number NCT01194596.Data are available on reasonable request. Patient level data, the full dataset and statistical code are available from the corresponding author (fmartin.tgn.ics@gencat.cat).