PT  - JOURNAL ARTICLE
AU  - Francisco Martin-Lujan
AU  - Josep Basora-Gallisa
AU  - Felipe Villalobos
AU  - Nuria Martin-Vergara
AU  - Estefania Aparicio-Llopis
AU  - Irene Pascual-Palacios
AU  - Antoni Santigosa-Ayala
AU  - Roxana-Elena Catalin
AU  - Cristina Rey-Reñones
AU  - Rosa Solà
ED  - ,
TI  - Effectiveness of a motivational intervention based on spirometry results to achieve smoking cessation in primary healthcare patients: randomised, parallel, controlled multicentre study
AID  - 10.1136/jech-2020-216219
DP  - 2021 Oct 01
TA  - Journal of Epidemiology and Community Health
PG  - 1001--1009
VI  - 75
IP  - 10
4099  - http://jech.bmj.com/content/75/10/1001.short
4100  - http://jech.bmj.com/content/75/10/1001.full
SO  - J Epidemiol Community Health2021 Oct 01; 75
AB  - Objective This 12-month study in a primary healthcare network aimed to assess the effectiveness of usual smoking cessation advice compared with personalised information about the spirometry results.Design Randomised, parallel, controlled, multicentre clinical trial.Setting This study involved 12 primary healthcare centres (Tarragona, Spain).Participants Active smokers aged 35–70 years, without known respiratory disease. Each participant received brief smoking cessation advice along with a spirometry assessment. Participants with normal results were randomised to the intervention group (IG), including detailed spirometry information at baseline and 6-month follow-up or control group (CG), which was simply informed that their spirometry values were within normal parameters.Main outcome Prolonged abstinence (12 months) validated by expired-CO testing.Results Spirometry was normal in 571 patients in 571 patients (45.9% male), 286 allocated to IG and 285 to CG. Baseline characteristics were comparable between the groups. Mean age was 49.8 (SD ±7.78) years and mean cumulative smoking exposure was 29.2 (±18.7) pack-years. Prolonged abstinence was 5.6% (16/286) in the IG, compared with 2.1% (6/285) in the CG (p=0.03); the cumulative abstinence curve was favourable in the IG (HR 1.98; 95% CI 1.29 to 3.04).Conclusions In active smokers without known respiratory disease, brief advice plus detailed spirometry information doubled prolonged abstinence rates, compared with brief advice alone, in 12-month follow-up, suggesting a more effective intervention to achieve smoking cessation in primary healthcare.Trial registration number NCT01194596.Data are available on reasonable request. Patient level data, the full dataset and statistical code are available from the corresponding author (fmartin.tgn.ics@gencat.cat).