TY - JOUR T1 - Ethnicity and risk of diagnosed dementia after stroke: a cohort study using the Clinical Practice Research Datalink JF - Journal of Epidemiology and Community Health JO - J Epidemiol Community Health SP - 114 LP - 119 DO - 10.1136/jech-2019-212825 VL - 74 IS - 2 AU - Suhail Ismail Shiekh AU - Harriet Forbes AU - Rohini Mathur AU - Liam Smeeth AU - Neil Pearce AU - Charlotte Warren-Gash Y1 - 2020/02/01 UR - http://jech.bmj.com/content/74/2/114.abstract N2 - Introduction The UK has over 1.2 million stroke survivors. Stroke is a major risk factor for dementia, and along with other risk factors such as hypertension and diabetes, is more common among Black, Asian and other ethnic minorities (BAME). We aimed to explore whether diagnosed dementia differed by ethnicity among adult stroke survivors.Methodology Using the UK Clinical Practice Research Datalink and linked hospital data, we conducted a cohort study among patients aged ≥40 years who had an incident stroke between 2005 and 2016. We fitted multivariable Cox proportional hazard models to estimate ethnic differences in the risk of poststroke dementia, adjusting for major clinical and social confounders.Results Our cohort comprised 45 474 stroke survivors (mean age 72.6 years, 49% female), of whom 95.7% were White, 2.0% South Asian, 1.2% Black and 1.1% of Mixed/Other ethnicity. Of these, 4624 (10.2%) were diagnosed with poststroke dementia over a median follow-up of 3.26 years. Compared with the White ethnic group, those of Black ethnicity were 42% more likely to be diagnosed with dementia (adjusted HR 1.42, 95% CI 1.05 to 1.93). There was no association between any other ethnic group and poststroke dementia diagnosis.Discussion There was good evidence that those of Black ethnicity had higher risk of diagnosed dementia poststroke. Further understanding of the mechanisms of this relationship could help target interventions at communities most at risk of dementia poststroke. ER -