TY - JOUR T1 - Cause-specific mortality in Swedish males diagnosed with non-psychotic mental disorders in late adolescence: a prospective population-based study JF - Journal of Epidemiology and Community Health JO - J Epidemiol Community Health SP - 582 LP - 588 DO - 10.1136/jech-2018-210461 VL - 72 IS - 7 AU - Malin Henriksson AU - Jenny Nyberg AU - Linus Schiöler AU - Gunnel Hensing AU - Georg H Kuhn AU - Mia Söderberg AU - Kjell Torén AU - Jesper Löve AU - Margda Waern AU - Maria Åberg Y1 - 2018/07/01 UR - http://jech.bmj.com/content/72/7/582.abstract N2 - Background While risk of premature death is most pronounced among persons with severe mental illness, also milder conditions are associated with increased all-cause mortality. We examined non-psychotic mental (NPM) disorders and specific causes of natural death in a cohort of late adolescent men followed for up to 46 years.Methods Prospective cohort study of Swedish males (n=1 784 626) who took part in structured conscription interviews 1968–2005. 74 525 men were diagnosed with NPM disorders at or prior to conscription. Median follow-up time was 26 years. HRs for cause-specific mortality were calculated using Cox proportional hazards models.Results Risks in fully adjusted models were particularly elevated for death by infectious diseases (depressive and neurotic/adjustment disorders (HR 2.07; 95% CI 1.60 to 2.67), personality disorders (HR 2.90; 95% CI 1.96 to 4.28) and alcohol-related and other substance use disorders (HR 9.02; 95% CI 6.63 to 12.27)) as well as by gastrointestinal causes (depressive and neurotic/adjustment disorders (HR 1.64; 95% CI 1.42 to 1.89), personality disorders (HR 2.77; 95% CI 2.27 to 3.38) and alcohol-related/substance use disorders (HR 4.41; 95% CI 3.59 to 5.42)).Conclusion Young men diagnosed with NPM disorders had a long-term increased mortality risk, in particular due to infectious and gastrointestinal conditions. These findings highlight the importance of early preventive actions for adolescents with mental illness. ER -