TY - JOUR T1 - Modelling the effects of low indoor temperatures on the lung function of children with asthma JF - Journal of Epidemiology and Community Health JO - J Epidemiol Community Health SP - 918 LP - 925 DO - 10.1136/jech-2013-202632 VL - 67 IS - 11 AU - Nevil Pierse AU - Richard Arnold AU - Michael Keall AU - Philippa Howden-Chapman AU - Julian Crane AU - Malcolm Cunningham AU - the Heating Housing and Health Study Group Y1 - 2013/11/01 UR - http://jech.bmj.com/content/67/11/918.abstract N2 - Introduction While many epidemiological studies have shown that low outdoor temperatures are associated with increased rates of hospitalisation and mortality (especially for respiratory or cardiovascular disease), very few studies have looked at the association between indoor temperatures and health. Such studies are clearly warranted, as people have greater exposure to the indoor environment than the outdoor environment. Objectives To examine the relationship between various metrics of indoor temperature and lung function in children with asthma. Our specific research questions were: (1) In which room of the home is temperature most strongly associated with lung function? (2) Which exposure metric best describes the relationship between indoor temperature and lung function? (3) Over what lag/time period does indoor air temperature affect lung function most strongly? Methods The Heating Housing and Health Study was a randomised controlled trial that investigated the effect of installing heaters in the homes of children with asthma. This study collected measurements of lung function (daily) and indoor temperature (hourly). Lung function and indoor temperature were measured for 309 children over 12 049 child-days. Statistical models were fitted to identify the best measures and metrics. Results The strongest association with lung function was found for the severity of exposure to low bedroom temperatures averaged over the preceding periods of 0–7 to 0–12 days. A 1°C increase in temperature was associated with an average increase of 0.010, 0.008, 10.06, 12.06, in our four measures of lung function (peak expiratory flow rate (PEFR) morning, PEFR evening, forced expiratory volume in 1 s (FEV1) morning and FEV1 evening). Conclusions Indoor temperatures have a small, but significant, association with short-term variations in the lung function of children with asthma. ER -