RT Journal Article SR Electronic T1 Heaviness, health and happiness: a cross-sectional study of 163066 UK Biobank participants JF Journal of Epidemiology and Community Health JO J Epidemiol Community Health FD BMJ Publishing Group Ltd SP 340 OP 348 DO 10.1136/jech-2013-203077 VO 68 IS 4 A1 Zia Ul-Haq A1 Daniel F Mackay A1 Daniel Martin A1 Daniel J Smith A1 Jason M R Gill A1 Barbara I Nicholl A1 Breda Cullen A1 Jonathan Evans A1 Beverly Roberts A1 Ian J Deary A1 John Gallacher A1 Matthew Hotopf A1 Nick Craddock A1 Jill P Pell YR 2014 UL http://jech.bmj.com/content/68/4/340.abstract AB Background Obesity is known to increase the risk of many diseases and reduce overall quality of life. This study examines the relationship with self-reported health (SRH) and happiness. Methods We conducted a cross-sectional study of the 163 066 UK Biobank participants who completed the happiness rating. The association between adiposity and SRH and happiness was examined using logistic regression. SRH was defined as good (excellent, good), or poor (fair, poor). Self-reported happiness was defined as happy (extremely, very, moderately) or unhappy (moderately, very, extremely). Results Poor health was reported by 44 457 (27.3%) participants. The adjusted ORs for poor health were 3.86, 2.92, 2.60 and 6.41 for the highest, compared with lowest, deciles of Body Mass Index, waist circumference, waist to hip ratio and body fat percent, respectively. The associations were stronger in men (p<0.001). Overall, 7511 (4.6%) participants felt unhappy, and only class III obese participants were more likely to feel unhappy (adjusted OR 1.33, 95% CI 1.15 to 1.53, p<0.001) but the associations differed by sex (p<0.001). Among women, there was a significant association between unhappiness and all levels of obesity. By contrast, only class III obese men had significantly increased risk and overweight and class I obese men were less likely to be unhappy. Conclusions Obesity impacts adversely on happiness as well as health, but the association with unhappiness disappeared after adjustment for self-reported health, indicating this may be mediated by health. Compared with obese men, obese women are less likely to report poor health, but more likely to feel unhappy.