RT Journal Article SR Electronic T1 P2-170 Direct estimation of tobacco-attributable cancer mortality in Poland JF Journal of Epidemiology and Community Health JO J Epidemiol Community Health FD BMJ Publishing Group Ltd SP A268 OP A268 DO 10.1136/jech.2011.142976j.5 VO 65 IS Suppl 1 A1 Manczuk, M YR 2011 UL http://jech.bmj.com/content/65/Suppl_1/A268.1.abstract AB Introduction The aim of the present study was to estimate the number cancer deaths, and their proportion over total deaths in that age ranges, attributable to tobacco in Poland.Methods The calculation of tobacco-attributable mortality was based on the combination of RRs and prevalence of exposure. The selection of tobacco-related diseases and causes of death relied on recent comprehensive reviews by the International Agency for Research on Cancer [IARC, 2004] and the U.S. Government [USDHHS, 2004]. The set of RRs was derived from the Cancer Prevention Study II (CPS-II). Data on smoking prevalence come from national survey studies. Data on cancer mortality separately for 11 cancer sites related to tobacco were obtained form National Cancer Registry. To introduce into the model the latency effect demonstrated for most chronic health effects of tobacco, period of 20 years latency between exposure and death was implemented.Results In 2005 in Poland there were 24 222 cancer deaths among men (197.3/100 000) and 5177 among women (35.8/100 000) attributed to active tobacco smoking. Among eleven cancer sites attributed to tobacco, the biggest killer was lung cancer with 15 478 deaths among men (60.4/100 000) and 3538 deaths among women (10.7/100 000).Conclusion Direct estimations (based on smoking prevalence) can be successfully used to calculate tobacco burden. In Poland in tobacco-related cancers kill substantial number of men and women every year. Quantifying the size of tobacco burden gives arguments for evidence-based tobacco control intervention.