TY - JOUR T1 - Length of gestation is associated with mortality from cerebrovascular disease JF - Journal of Epidemiology and Community Health JO - J Epidemiol Community Health SP - 473 LP - 474 DO - 10.1136/jech.2004.026518 VL - 59 IS - 6 AU - Ilona Koupil AU - David A Leon AU - Hans O Lithell Y1 - 2005/06/01 UR - http://jech.bmj.com/content/59/6/473.abstract N2 - Recent studies reported on increased levels of adult cardiovascular risk factors in subjects born prematurely,1 and on interactions between length of gestation and size at birth in their effect on cortisol metabolism,2 and blood pressure.3 The effect of fetal growth rate and the length of gestation on circulatory disease are explored in this study. In a cohort of 14 193 men and women born in Uppsala in 1915–1929, we studied the associations of fetal growth rate and length of gestation with the risk of death from ischaemic heart disease (ICD 7: 420–422; 8 and 9: 410–414; 10: I20–25) and cerebrovascular disease (ICD 7: 330–334; 8 and 9: 430–438, 10: I60–69). Occlusive strokes include ICD7: 332–334, ICD8: 432–436, ICD9: 433–436 and ICD10: I63–66. Data on deaths and emigrations were obtained by linkage to the population and death registers. Socioeconomic circumstances at birth and neonatal characteristics, including gestational age (based on last menstrual period), were available for 96% of the subjects from hospital records. Data on social circumstances in adulthood included subjects’ own social group, education, marital status, and household car ownership from 1960 census and were available for 96% of … ER -