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Effects of Housing First approaches on health and well-being of adults who are homeless or at risk of homelessness: systematic review and meta-analysis of randomised controlled trials
  1. Andrew J Baxter1,2,
  2. Emily J Tweed2,
  3. Srinivasa Vittal Katikireddi2,
  4. Hilary Thomson2
  1. 1College of Medicinal, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
  2. 2MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK
  1. Correspondence to Andrew J Baxter, MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow G2 3AX, UK; a.baxter.1{at}


Background Homelessness is associated with poor health. A policy approach aiming to end homelessness across Europe and North America, the ‘Housing First’ (HF) model, provides rapid housing, not conditional on abstinence from substance use. We aimed to systematically review the evidence from randomised controlled trials for the effects of HF on health and well-being.

Methods We searched seven databases for randomised controlled trials of interventions providing rapid access to non-abstinence-contingent, permanent housing. We extracted data on the following outcomes: mental health; self-reported health and quality of life; substance use; non-routine use of healthcare services; housing stability. We assessed risk of bias and calculated standardised effect sizes.

Results We included four studies, all with ‘high’ risk of bias. The impact of HF on most short-term health outcomes was imprecisely estimated, with varying effect directions. No clear difference in substance use was seen. Intervention groups experienced fewer emergency department visits (incidence rate ratio (IRR)=0.63; 95% CI 0.48 to 0.82), fewer hospitalisations (IRR=0.76; 95% CI 0.70 to 0.83) and less time spent hospitalised (standardised mean difference (SMD)=−0.14; 95% CI −0.41 to 0.14) than control groups. In all studies intervention participants spent more days housed (SMD=1.24; 95% CI 0.86 to 1.62) and were more likely to be housed at 18–24 months (risk ratio=2.46; 95% CI 1.58 to 3.84).

Conclusion HF approaches successfully improve housing stability and may improve some aspects of health. Implementation of HF would likely reduce homelessness and non-routine health service use without an increase in problematic substance use. Impacts on long-term health outcomes require further investigation.

Trial registration number CRD42017064457

  • homelessness
  • housing first
  • health
  • mental illness
  • substance use

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  • Patient consent for publication Not required.

  • Contributors SVK and ET proposed the need for this review. AJB conducted the search, screening, data extraction and data analysis stages. ET replicated the screening process and checked data extracted and analysed for errors. All authors read and approved the final manuscript.

  • Funding ET, SVK and HT are funded by the Medical Research Council (MC_UU_12017/13 and MC_UU_12017/15) and Chief Scientist Office (SPHSU13 and SPHSU15). SVK is also funded by a NRS Scottish Senior Clinical Fellowship (SCAF/15/02). ET is also funded by a Chief Scientist Office Clinical Academic Fellowship (CAF/17/11).

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data sharing statement Details of calculations and risk of bias assessment are available on request from AJB.