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Mortality at ages 50-59 and deprivation at early and late stages of the lifecourse in Wales
  1. Maria Fenicia Vescio1,
  2. Sara T Brookes2,
  3. Jonathan Sterne2,
  4. Laurence Moore3,
  5. Giovanni Rezza1,
  6. George Davey Smith2
  1. 1 Istituto Superiore di Sanità, Italy;
  2. 2 University of Bristol, United Kingdom;
  3. 3 University of Cardiff, United Kingdom
  1. E-mail: vescio{at}


Background: Most of the studies have examined association between mortality and deprivation at only one point in time. However risk accumulates over the life course.

Aims: Explain inequalities in total and cause specific mortality between geographical areas in relation to the life style and health behaviours of the resident populations and the area levels of deprivation in 1981 and in 1921-1940.

Study design: Ecological.

Methods: Data on health behaviour from the 1985 Heartbeat Wales Community Survey were evaluated in light of Welsh mortality rates for the period 1981-1999, 1981 census data on socio-economic position and the infant mortality rates in 1921 - 1940. Negative binomial models were carried out to investigate the district level association of mortality with deprivation (infant mortality in 1921-1940, Carstairs score in 1981, combined index of deprivation) independently from the personal habits and characteristics of the resident population.

Results: There was an increased risk of death in deprived areas as opposed to more wealthy ones. Both infant mortality (a proxy of material deprivation during the time in which the 50-59 year old individuals were born or were children) and Carstairs scores (a proxy of deprivation during adulthood) were strongly associated with recent mortality. Deprivation had stronger effects in women than in men, the only exception being the effects of later life deprivation on lung cancer.

Discussion: Area characteristics at different points of time may help to explain geographical inequality in mortality.

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