Background Some groups of the population are known to be less likely to access offers of vaccination, and, as a result, suffer a higher burden of preventable communicable disease. Less is known about what works to address this inequality in uptake. The present intervention involved utilising various forms of intelligence to maximise opportunities for access in target populations, coupled with culturally sensitive promotion.

Methods The project used a mixed methods approach, informed and evaluated using both quantitative and qualitative data. Lower Super Output Area (LSOA) data showing spatial variation in vaccine uptake; variation below county level by deprivation, gender, age and clustering of low vaccination coverage was analysed to identify priority geographical areas and population cohorts for this intervention. This data, triangulated with context specific information and in-depth local knowledge from multi-agency collaborators, informed the identification and selection of trusted and accessible community venues for mobile pop-up vaccination clinics and the design of a locally appropriate vaccination offer.

Results Quantitative data from the mobile pop-up vaccination clinics showed that 10, 253 vaccinations were delivered between May and November 2021. This shows increases ranging between 257% -1,194% compared to the 7 day average in those LSOAs. Of the vaccinations given 78% were 1st dose with 18–29 yr highest cohort.

Qualitative data, statements from people attending clinics and feedback from staff and host organisations showed local access to vaccinations suited people’s daily work or caring routines. People cited the convenience and ease of attending without going through an online booking system and the efficiency of the pop-up delivery as reasons for attending. This positive experience prompted requests for further vaccinations and health interventions to be delivered this way.

Conclusion The combination of LSOA data with qualitative and context specific multiagency insights proved very effective for planning location of pop-up clinics. The Leaving No-one Behind approach added significant value, increasing ease of opportunity and equity of access, resulting in increased vaccination rates in hard to reach communities.

Qualitative insights provided evidence that local communities liked to attend clinics opportunistically at their convenience in local settings.

Priority and relevance The Leaving No-one Behind approach, particularly via the combination of granular quantitative data and the enhancement of context specific qualitative data proved highly effective. Further research could increase understanding of the complex interplay of socio-environmental context at place and the impact on the delivery of health programmes.

Further research opportunities including cost benefit analysis would also be beneficial.