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Fluoride exposure and indicators of thyroid functioning: study design and data analysis considerations
  1. Declan Timothy Waugh
  1. Correspondence to Declan Timothy Waugh, EnviroManagement Services, Cork, Ireland; declan{at}

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Barberio et al 1 reported that there was no evidence of a relationship between fluoride exposure and the diagnosis of a thyroid condition among a subsample of respondents available from Statistics Canada’s Canadian Health Measures Survey. On review, however, their data show that the mean urinary fluoride (UF) level in patients with primary hypothyroidism was 0.60 mg/L compared with 0.55 mg/L for individuals without this condition. In other words, the mean UF levels in respondents with primary hypothyroidism were higher than without. However, it is the reported ranges of UF levels from either groups that is particularly revealing. For example, among individuals with primary hypothyroidism, UF …

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  • Contributors DTW is the sole contributor.

  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.