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Is participation contagious? Evidence from a household vector control campaign in urban Peru
  1. Alison M Buttenheim1,
  2. Valerie Paz-Soldan2,
  3. Corentin Barbu3,
  4. Christine Skovira3,
  5. Javier Quintanilla Calderón4,
  6. Lina Margot Mollesaca Riveros4,
  7. Juan Oswaldo Cornejo4,
  8. Dylan S Small5,
  9. Christina Bicchieri6,
  10. Cesar Naquira7,
  11. Michael Z Levy3
  1. 1University of Pennsylvania School of Nursing, Family and Community Health, Philadelphia, Pennsylvania, USA
  2. 2Department of Global Health Systems and Development, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA
  3. 3Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
  4. 4Universidad Peruana Cayetano Heredia, Arequipa, Peru
  5. 5Department of Statistics, The Wharton School, University of Pennsylvania, Philadelphia, Pennsylvania, USA
  6. 6Department of Philosophy, The Wharton School, University of Pennsylvania, Philadelphia, Pennsylvania, USA
  7. 7Universidad Peruana Cayetano Heredia, Lima, Peru
  1. Correspondence to Dr Alison M Buttenheim, University of Pennsylvania School of Nursing, Family and Community Health 235L Fagin Hall, 418 Curie Boulevard, Philadelphia, PA 19104, USA; abutt{at}nursing.upenn.edu

Abstract

Objectives High rates of household participation are critical to the success of door-to-door vector control campaigns. We used the Health Belief Model to assess determinants of participation, including neighbour participation as a cue to action, in a Chagas disease vector control campaign in Peru.

Methods We evaluated clustering of participation among neighbours; estimated participation as a function of household infestation status, neighbourhood type and number of participating neighbours; and described the reported reasons for refusal to participate in a district of 2911 households.

Results We observed significant clustering of participation along city blocks (p<0.0001). Participation was significantly higher for households in new versus established neighbourhoods, for infested households, and for households with more participating neighbours. The effect of neighbour participation was greater in new neighbourhoods.

Conclusions Results support a ‘contagion’ model of participation, highlighting the possibility that one or two participating households can tip a block towards full participation. Future campaigns can leverage these findings by making participation more visible, by addressing stigma associated with spraying, and by employing group incentives to spray.

  • Communicable Diseases
  • Control of DIseases
  • Tropical Health
  • Developing Countr
  • Epidemiology

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Introduction

Community participation in health programmes has been a core goal of health planners and practitioners since the 1978 Alma Ata Declaration.1 Many health programmes rely on household and community participation to achieve key outcomes. In the case of vector control, high rates of household participation are critical to the success of door-to-door campaigns that target mosquitoes,2 triatomine bugs3 and other insects of medical importance.4 Low participation rates decrease the effectiveness and efficiency of disease control efforts and, at the same time, may signal that communities are not invested in the campaign aims or strategies.

The goal of this study was to describe patterns and predictors of participation in a Chagas disease vector control campaign in Peru. Chagas disease is a principal cause of morbidity and mortality in the Americas.5 The economic burden of Chagas disease is estimated to exceed that of cervical cancer, rotavirus or Lyme disease.6 More than eight million people are infected with Trypanosoma cruzi, the parasitic agent of the disease.7 In the southern part of South America, T cruzi is transmitted primarily by Triatoma infestans insect vectors. Since 1991, T infestans has been the target of a widespread control programme known as the Southern Cone Initiative. Through the efforts of this initiative, the disruption of T cruzi transmission by T infestans has been declared in Chile,8 Brazil9 and Uruguay.10 Vector control campaigns are ongoing in southern Peru where, in contrast to other areas, the vector is an urban rather than a rural problem.11 ,12

The control of Chagas disease depends critically on successful indoor residual spraying campaigns paired with long-term surveillance to address vector return and reinfestation.13 ,14 Recent data from a vector control campaign in urban Arequipa, Peru indicate that participation was only 66%, which may be insufficient to control triatomine insects and to disrupt T cruzi transmission. Declining participation in urban areas threatens the success of the Peru campaign and ultimately that of the Southern Cone Initiative. Understanding the determinants of household participation is therefore an important step in designing new interventions to ensure campaign success.

To inform campaign improvements, we studied the correlates of participation in one district of Arequipa, Peru. Our analysis was guided by the Health Belief Model, which models health-related behaviours as a function of the perceived threat of the related health condition, perceived benefits and barriers and cues to action.15 We first hypothesised that the observable participation of neighbours would be an important cue to action—in other words, participation may be ‘contagious’ along city blocks. Another obvious cue to action is vector infestation, which we hypothesised would also be associated with participation. We further hypothesised that the influence of neighbour participation may depend on infestation status: households that are already infested may be less motivated by neighbour participation than uninfested households. Finally, we assessed barriers to participation reported in a neighbourhood with low participation rates.

Methods

In 2003, the Ministry of Health (MOH) in Arequipa, Peru initiated a large-scale insecticide application campaign with the aim of eliminating T cruzi transmission by T infestans. The campaign proceeds district by district in three phases. In the preliminary survey phase, prior to the application of insecticide, all houses are surveyed for the presence of T infestans. In the attack phase, sensibilizadoras (health promoters) visit each household, explain the risks of Chagas disease and the role of the insect in its transmission, and encourage residents to agree to insecticide application. Sensibilizadoras also explain how to prepare the home for insecticide spraying by moving furniture away from walls and stowing bed linens, food and kitchenware. The following day, a exterminator applies insecticide in the home and around the peridomestic animal enclosures. The process is repeated 6 months later. In the surveillance phase, health promoters and campaign staff monitor sprayed areas for vector reinfestation.

The Arequipa campaign stresses the specific objective of convincing community members to accept insecticide spraying; in the community participation literature, this approach is termed as ‘target-oriented’ frame.16 ,17 In this context, we adopt a narrow definition of participation: household consent to and completion of insecticide spraying during the first spray of the attack phase. Non-participation may be due to several reasons: households may refuse to participate, be away from home when the campaign visits, fail to adequately prepare the home for spraying or not provide access to locked rooms (exterminators will only spray if all rooms can be accessed).

We used data from the preliminary and attack phases of the campaign in the Mariano Melgar (MM) district of Arequipa collected between 2010 and 2012. The district is home to approximately 9500 households and three distinct neighbourhood types: established, new and land invasion. Land invasion neighbourhoods emerge when recent migrants organise to ‘invade’ undeveloped land and construct basic housing from cheap materials. If the settlers are not forcibly removed, housing stock is improved over time and residents may receive land titles. At this point, a land invasion becomes a ‘new neighbourhood’ (pueblo joven). As new neighbourhoods mature into established neighbourhoods with wealthier residents, homes become larger and gain permanent utility connections. In our study, established neighbourhoods were founded several decades ago and tended to have wealthier residents. New neighbourhoods were founded in the 1980s and 1990s during a time of mass rural to urban migration in Peru. The recent land invasions in our study setting originated around 2000, but did not have any triatomine bugs during the preliminary survey phase and were therefore not included in the spray campaign or in these analyses.

Neighbour participation and infestation status as cues to action

We first looked for spatial patterns in participation using campaign data from the first round of the attack phase in Pueblo Tradicional (PT), the largest neighbourhood in MM (n=2911 households). We looked for statistically significant runs of participation along blocks, with a ‘run’ defined as a series of similar responses (ie, participation or non-participation). We used the Siegel and Castellan18 runs test, which assesses the frequency of runs and compares the observed frequency to that expected by chance. The runs test requires that we linearise the city block; we followed the numbering assigned to households by the MOH to order the insecticide application. The first and last houses were therefore not considered neighbours even though they may have been contiguous.

Our second analysis exploited a transect sample (2 blocks wide by 2 km long) of MM that includes established and new neighbourhoods. We used detailed vector infestation data (collected by our study team during the preliminary survey in 2009–2010) and campaign participation data (collected during the first spray in 2011). In the preliminary survey, data were collected from 381 of the 443 households in the transect. Using a logistic regression model, we estimated participation as a function of: the number of immediate neighbours who participated in the campaign (0,1,2); a binary measure of infestation in the house (1, infested: any insects found during the preliminary survey; 0, uninfested: no insects found during the preliminary survey); and the interaction of neighbour participation and infestation. We first fitted this model on the full transect sample controlling for neighbourhood type (established vs new). To test hypotheses based on campaign observations and our knowledge of neighbourhood evolution, we then stratified the sample by neighbourhood type to assess differences in the relationship between infestation status, neighbour participation and household participation in established versus new neighbourhoods.

Perceived barriers to participation

Low participation in the first round of insecticide application motivated the MOH to record reported reasons for non-participation during the second round of insecticide application. We used data from 534 visits to 446 non-participating households in PT to assess perceived barriers to participation. Householders could provide more than one reason for refusal during any given visit, and 75 households (17%) were visited more than one time. All reasons mentioned by households at any visit were included in the analysis. Interviewers coded reasons for refusal according to a nine-category coding scheme developed from open-ended responses about non-participation collected previously in nearby neighbourhoods of MM. We analysed the distribution of reasons for refusal reported during the second spray in PT among this sample of households.

Results

Participation in the first round of the attack phase in MM was 66% (6336 of 9579 total properties). We observed geographical clustering of participation (figure 1), including significant runs of participation along blocks (p<0.0001, Siegel-Castellan runs test). While this test of spatial autocorrelation does not imply that neighbour behaviour influences participation decisions, it does suggest some social contagion.

Figure 1

Participation in the first round of attack phase of the Chagas disease vector control campaign, Mariano Melgar District, Arequipa, Peru, 2011. Grey dots denote participation, whereas black dots denote non-participation.

Participation in the transect sample was 77% (340 of 433 total properties), higher than in the MM overall. However, there were stark differences in participation rates along the transect. Most notably, participation was higher in new versus established neighbourhoods and for infested versus uninfested households (figure 2). Furthermore, the upward slope for the uninfested households in new neighbourhoods in figure 2 indicates an association between the number of neighbours participating and household participation in this subgroup: the probability of participation was 50% for households with no neighbours participating versus 92% for households with both adjacent neighbours participating. Within neighbourhood type, infested households were more likely to participate than uninfested households, although the gap narrowed as more neighbours participated. Among infested households, those in new neighbourhoods participated more than those in established neighbourhoods.

Figure 2

Participation in the spray campaign by infestation status, neighbourhood and immediate neighbour participation, Mariano Melgar, 2011. Analysis excludes cells with fewer than five households (infested house, new neighbourhood, 0 neighbours participating; and infested house, established neighbourhood, 0 neighbours participating).

We confirmed the association of household and neighbour participation through regression models (table 1). In Model 1, each additional participating neighbour more than doubled the odds of participating, while infestation increased the odds of participating more than 10-fold. The negative interaction term indicates that the influence of neighbour participation was attenuated in infested households. The model also shows that households in established neighbourhoods had, on average, half the odds of participating compared with households in new neighbourhoods. In Models 2 and 3, we stratified by neighbourhood type. Results confirmed that neighbour participation was a significant predictor of household participation only in new neighbourhoods (OR=3.79, p<0.01); within new neighbourhoods, neighbour participation was only a significant predictor of household participation among uninfested households (OR for interaction of neighbour participation and infestation was 0.14, p<0.10). Infestation also significantly increased the odds of participation in new neighbourhoods by almost 40 times. Our results suggest that neighbour participation and infestation are important cues to action in new neighbourhoods, but less so in established neighbourhoods, thus motivating our analysis of perceived barriers to participation for these households.

Table 1

ORs from logistic models predicting participation in a Chagas disease vector control campaign as a function of neighbour participation, infestation status and neighbourhood type, Mariano Melgar District Transect Sample, Arequipa, Peru, 2010 (N=381 households)

Figure 3 presents the distribution of reasons given for non-participation by 446 households in PT in 2012. The dominant reason was the inability to wait at home for the exterminators or having to go to work (36%). Two other commonly stated reasons were concerns about allergies (20%) and renters not willing to consent to spray on behalf of a landlord (18%). Less frequently mentioned were concerns about letting strangers into the house (9%), locked rooms with no key available (8%), not wanting to move furnishings to prepare for spraying (8%), and concerns about the insecticide staining the walls (3%). An additional 14% of responses fell into the ‘other’ category; the most frequently mentioned reason in this group of responses was the lack of bugs in the home. In addition, 9% of responses indicated ‘no reason’ for refusal, suggesting that householders were unwilling to state the true reasons for refusal, were not the main decision-makers in the household, or were so little engaged in the vector control campaign that a clear reason for refusal could not be articulated.

Figure 3

Reasons given for refusing indoor residual spray by households in the community of Pueblo tradicional, Mariano Melgar, Arequipa, Peru (N=446 households). Households could provide more than one reason per visit, and 17% of households provided reasons for refusal on more than one visit. See text for description of each reason for refusal.

Discussion

Our results suggest that participation in the campaign may have been influenced by neighbour participation. Household participation was clustered spatially, suggesting that neighbour participation may be an important cue to action. While the runs of participation we observed could have been due to spatial patterns of urban vector infestation19 or other sociodemographic predictors of participation, the positive association between neighbour participation and each household's participation decision was robust to the addition of vector infestation and neighbourhood type controls in multivariate models. Our results highlight the potential to nudge others towards participation if just one or two households assent to insecticide application. Conversely, one or two refusals on a block may threaten the participation of many additional households.

Much of the previous work on vector control campaign participation has focused on surveillance or on prevention activities related to building materials and environmental hygiene20–23; our results contribute additional evidence on participation in indoor residual spraying activities, a less-studied topic. Several prior studies have also identified reasons for refusal that map to the Health Belief Model: lack of knowledge of the disease, low perceived risk, poor communication by control campaign staff, distrust of government services, stigma associated with vectors or with control activities and perceived low efficacy and high cost of interventions.24–26 Householders may be particularly wary when campaign activities require workers to enter the home.24 ,27

Higher rates of participation have been observed in campaigns across several countries when the community is engaged early in the process; when control activities are integrated with primary healthcare and development activities; when campaigns include direct, face-to-face contact with public health officials and community health workers; and when householders are given choices about when and how to implement control activities.20 ,28 Positive engagement and incentives have also proved more effective than punitive measures such as fines or citations.22 These findings are consistent with broader work on community participation showing that participatory approaches that empower communities to identify health problems and design solutions in partnership with government programmes may be more successful.29

While the current Chagas vector control campaign in Arequipa already employs many of these lessons, participation remains low in urban areas, and a better understanding of the determinants of participation is needed. The present study contributes to that understanding in several important ways: first, we observed less participation among households in the wealthier established neighbourhoods compared with poorer new communities. This is to be expected given the lower prevalence of vector infestation, an important cue to action. However, even when controlling for vector infestation, lower participation rates persisted in established neighbourhoods. We propose both an economic and a social mechanism for this difference: economically, campaign participation may impose a greater perceived burden on wealthier individuals who have larger households with more belongings to move and who may assign a higher opportunity cost to their time. Socially, wealthier households may perceive more social stigma associated with insecticide application, which may be construed as a public signal of vector infestation.

We make a second key contribution to the literature on the influence of social norms on health-related behaviour (observed in many other contexts30 ,31) by identifying two important effect modifiers in the relationship between descriptive norms and participation: first, we find that the influence of descriptive norms (ie, observable neighbour participation) is weaker for households with stronger cues to action in the form of visible insect infestation. Second, social influence appears to be stronger in new versus established neighbourhoods. This may be due to the greater importance of social ties for managing risk and transmitting information in poor neighbourhoods.32 This finding is consistent with how neighbourhoods evolved in the district as described above: in earlier stages of neighbourhood evolution, settlers are well organised. Social ties may then weaken in established neighbourhoods as individuals become less interdependent.

It is important to note here, however, that non-participating households do not report neighbour participation as a reason for refusal. We propose two reasons why neighbour participation was not raised by this sample of refusers. First, neighbour participation may be a stronger inducement to participate than neighbour non-participation is an inducement to not participate. The lack of responses about neighbour participation in this group of refusers may reflect that asymmetry. Second, people generally lack the ability to accurately report reasons for past behaviour, unless those motivations are highly salient and plausible.33 We therefore interpret the reported reasons for refusal as meaningful perceptions about barriers to participation, but do not interpret the failure to report neighbour participation as evidence against a contagion hypothesis.

Finally, our results inform interventions that may be effective in boosting participation in similar campaigns. Campaigns can first address some reasons for refusal through simple operational changes. For example, the most commonly stated reason for refusal in this study was the inability to wait at home for the spray brigades due to work commitments. Innovative scheduling schemes, such as guaranteed 2 h windows, evening appointments or priority scheduling for the first households to agree to spraying could address this concern. We caution, however, that such schemes could backfire if schedules are not feasible given the available personnel and infrastructure.

Other reasons stated for refusal are less amenable to campaign changes. In Arequipa, concerns about allergies (either a purported allergy to the insecticide or the concern that the insecticide would exacerbate existing allergies or asthma, particularly among children) were common. Previous research has shown that beliefs about allergies and asthma triggers are strongly held and culturally specific.34 ,35 These perceptions may therefore be difficult to change in the current campaign, even if a different insecticide were adopted or safety data were presented to concerned residents (both of which have been tried in the past with minimal results).

Another set of campaign innovations could leverage the observed importance of neighbour participation for household participation decisions, particularly in new neighbourhoods where social influence appears strong. Making participation more visible and salient, for example, by giving participating households posters or T-shirts, could amplify the effect of neighbour participation. Participation symbols that frame participation as beneficial to the community or to child health may further combat stigma associated with insecticide spraying.

To increase the perceived benefits of participation, lottery-based incentives could be introduced.36 ,37 Lotteries, common in Peru, provide immediate and tangible benefits to participation that may overcome some of the perceived costs of participation (time, inconvenience and stigma).38 A lottery may also motivate participation by decoupling participation from the stigma of vector infestation, and linking it instead with interest in the lottery.39 To leverage social norms and the motivation provided by lotteries, group lotteries could be introduced in which groups of contiguous households must all participate to be eligible for a lottery prize.40 As the response to lotteries may differ by socioeconomic status (with less wealthy households more likely to respond), rigorous trials evaluating the heterogeneous impact of these proposed interventions on participation are needed.

Our study leverages operational data from an ongoing vector control campaign to better understand patterns and determinants of participation. However, we note some important limitations. First, our conceptualisation of community and household participation in this study is fairly narrow. This is driven primarily by the structure of the vector control campaign, which seeks to convince households to accept the recommended insecticide spraying. We recognise that a broader investigation into community perceptions about the campaign and strategies to better engage the community in the design and implementation of the campaign could be very fruitful; however, these approaches are not currently part of the vector control campaign in Arequipa and hence beyond the scope of this study. Second, our data include spatial but not temporal aspects of household participation, and we are therefore not able to nail down the causal relationship between neighbour and household participation. Third, as non-participating households are often visited by multiple health promoters, we are not able to control the effect of individual health promoters on the participation decision. Fourth, there are certainly other covariates that are determinants or modifiers of participation that we were unable to measure, and our models can certainly be improved with additional studies. We were particularly unable to measure social networks, which may play an even more important role in the ‘contagiousness’ of participation than strictly geographical neighbourhood networks, and we were also not able to assess within-neighbourhood variation in socioeconomic status. Fifth, detecting vectors in households can be difficult, and our logistic regression models may suffer from misclassification of household infestation status, which would bias our estimates towards the null. Sixth, we had visited the households in the transect sample, which we used in our regression, many times and residents were much more cognizant of the dangers of Chagas disease and later participated more than residents outside the transect. This general increase in participation may also affect our regression analysis, most likely by biasing estimates towards the null if the increase in participation is uniform. Finally, our sample size for the analysis of refusal reasons is relatively small.

Household decisions about participation in vector control campaigns are multifactorial. Using operational data from a door-to-door vector control campaign in Peru, we have shown significant ‘runs’ of participation along city blocks. We have also demonstrated that household participation is associated with the participation of neighbours and that this relationship varies by household and neighbourhood characteristics. We have highlighted the diversity in stated reasons for non-participation, some of which can be addressed through changes in campaign operations. These results direct us to future interventions, which must decrease social and time costs to participation while increasing tangible and social benefits. The lessons learnt can be extended to other urban public health campaigns, particularly vector control campaigns against bed bug infestations and against mosquitoes that carry dengue, West Nile virus and malaria, where the social and spatial structure of city blocks links household decisions to community health outcomes.

What is already known on this subject?

  • Door-to-door vector control campaigns require high rates of household participation to succeed. To halt the transmission of Chagas disease in an endemic area of South America, it is important to understand why households accept or refuse indoor residual spraying.

What this study adds?

  • The decision to participate in a vector control campaign is complex. This study of a Chagas disease vector control campaign in Arequipa, Peru shows that household participation is associated with neighbour participation and that this relationship is stronger for lower income neighbourhoods and for households that are not infested with insect vectors. The study also highlights the reasons given by households for non-participation, some of which can be addressed through changes in campaign operations. These results direct us to future interventions, which must decrease the social and time costs of participation while increasing the tangible and social benefits.

Acknowledgments

The authors would like to thank the Chagas Disease Working Group in Arequipa comprised of staff of the Gerencia Regional de Salud en Arequipa (GERSA), Ministerio de Salud del Perú (MINSA), Dirección General de Salud de las Personas (DGSP), Estrategia Sanitaria Nacional de Prevención y Control de Enfermedades Metaxénicas y Otras Transmitidas por Vectores (ESNPCEMOTVS) and the Dirección General de Salud Ambiental (DIGESA). This work could never have been completed without the support and efforts of Fernando Málaga Chávez, Karina Oppe Álvarez, Andy Catacora Rospigliossi, Dr Juan Cornejo del Carpio, Dr Carlos Palacios Rosado, Dr Zeida Cáceres Cabana, Kate Levy and Malwina Niemierko. We thank Yage Wu and Eileen Wang for manuscript and translation assistance. In addition, the authors would like to acknowledge the past and present support of the Chagas Disease Control Programme in Arequipa from the Gobierno Regional de Arequipa, the Organización Panamericana de la Salud (OPS) and the Canadian International Development Agency (CIDA).

References

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Footnotes

  • Contributors AMB, MZL, CBa, VP-S, CBi and CN conceived the study. Data collection and management were overseen by CBa, JQC, LMMR and JOC. Analyses were conducted by AMB, MZL, CBa, DSS and CS. Additional methodological consultation was provided by DSS and CBi. AMB, MZL, CS, VP-S and CBa drafted the manuscript, tables and figures. All authors reviewed, edited and approved the final version of the manuscript.

  • Funding This work was supported by the National Institutes of Health grant number P50AI074285 and grant number K01AI079162, as well as by the University Research Foundation and the Global Engagement Fund of the University of Pennsylvania.

  • Competing interests None.

  • Ethics approval The University of Pennsylvania and Universidad Peruana Cayetano Heredia.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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