Aims The aim of this study was to investigate the epidemiologic features, survival analyses of colorectal cancer (CRC) and some related factors in a hospital of Tehran.

Subjects and Methods The type of study is case series descriptive study. 241 patients who registered from 2004 to 2009 were identified. Data collection was based on medical records and was completed using phone call. Survival analyses were constructed using the Kaplan–meier method. Multivariate analyses of related factors were conducted using Cox-regression analyses.

Results Mean age of participants was 59.7 year (SD=14.7), 22.4% were smoker and 24.5% have had family history of CRC. The rectum cancer was the common anatomic site of CRC and the majority of cancer grading were well differentiated status. 83.8% of participants were alive. The mean survival time for all patients was 56.5 months (±1.9). The lowest and highest mean survival time were 47.7 (±5.8) for cancer of secum and 61.1 (±3.2) for non-smokers respectively. The highest OR of survival 2.12 (95% CI 0.28 to 15.87) belongs to patients with rectum cancer.

Conclusion Our results showed that the mean survival time for CRC depends on some risk factors. It seems that, evaluation of these risk factors is necessary in lower age.