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Epidemiology and policy
SP3-72 Fruit and vegetables intake and plasma homocysteine levels among residents of municipality of SÃo Paulo
  1. R S Bigio,
  2. M A de Castro,
  3. J Steluti,
  4. V T Baltar,
  5. R M Fisberg,
  6. D M L Marchioni
  1. University of São Paulo, São Paulo, São Paulo, Brazil


Introduction The elevated concentration of plasma homocysteine (pHcy) was recently identified as risk factor for cardiovascular disease. Many studies have linked consumption of fruits and vegetables (F&V) with decreased of pHcy.

Objectives To investigate the pHcy concentrations according to consumption of F&V.

Methods A cross-sectional analysis was conducted in a sample of 291 individuals of both sexes, aged 12 y or over, that are from a population-based study performed in 2008–2010 in municipality of São Paulo. The consumption of fruits and vegetables were measured by two 24-h dietary recalls applied in non-consecutive days. Biochemical analysis of pHcy was conducted by the fluorescence polarisation immunoassay method. The cut-off point of pHcy used was <8 μmol/l for individuals younger than 15 y, <12 μmol/l for individuals with 15–65 y and <16 μmol/l for those over 65 y. The median consumption of F&V was described according to the pHcy levels (normal or high) in both sexes and analysed using the Kruskal–Wallis test.

Results The median of F&V was 97.9 g/day, with females exhibiting the higher consumption (134 g/day). Considering the WHO recommendation (>400 g/day), only 5.8% of individuals had adequate intake. There were no differences in the medians of intake of fruit and vegetables in females according to pHcy levels (normal: 112.88 g/day; high: 155.25 g/day). Unlike, we found lower consumption of F&V in males with hyperhomocysteinemia (normal: 96.80 g/day; high: 23.30 g/day; p=0.01).

Conclusion F&V intake is low in this population, especially in men with hyperhomocysteinemia. Therefore, it is necessary to encourage the F&V intake in this population.

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